2-(2-溴乙酰基)吡啶合成路线 （共 10 条）
反应条件
hydrogen bromide; bromine T=20 - 65°C; 2 h;
参考文献
Mjambili, Faith; Njoroge, Mathew; Naran, Krupa; De Kock, Carmen; Smith, Peter J.; Mizrahi, Valerie; Warner, Digby; Chibale, Kelly
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 2 p. 560 - 564
反应条件
pyridinium hydrobromide perbromide in tetrahydrofuran; chloroform
参考文献
Merck and Co., Inc.
Patent: US5854265 A1, 1998 ;
US 5854265 A
反应条件
N-bromosuccinmide; water; oxygen in ethyl acetate 10 h; Irradiation;
参考文献
Nobuta, Tomoya; Hirashima, Shin-Ichi; Tada, Norihiro; Miura, Tsuyoshi; Itoh, Akichika
Synlett, 2010 , # 15 p. 2335 - 2339
反应条件
water; hydrogen bromide; bromine Erwaermen des Reaktionsprodukts;
参考文献
Wunderlich
Journal fuer Praktische Chemie (Leipzig), 1955 , vol. <4> 2, p. 302,306
反应条件
formamide in methanol; ethanol; dimethyl-ether; water; hydrogen bromide; acetic acid
参考文献
The University of Toledo
Patent: US5639775 A1, 1997 ;
US 5639775 A
反应条件
1: in ethanol T=20°C; 1 h; 2: With sodium hydroxide in water
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 2 p. 560 - 564
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 53, # 39 p. 5265 - 5269
反应条件
1: N,N-dimethyl-formamide / 0 - 20 °C / |Inert atmosphere 2: eosin Y bis(tetrabutylammonium salt); N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C / |Irradiation; |Inert atmosphere View Scheme
参考文献
Yang, Deng-Tao; Meng, Qing-Yuan; Zhong, Jian-Ji; Xiang, Ming; Liu, Qiang; Wu, Li-Zhu
European Journal of Organic Chemistry, 2013 , # 33 p. 7528 - 7532
反应条件
cerium(III) chloride heptahydrate in poly(ethylene glycol)-400
T=20°C; 0.5 h;
参考文献
Emmadi, Narender Reddy; Atmakur, Krishnaiah
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 12 p. 1500 - 1504
反应条件
sodium azide in DMF (N,N-dimethyl-formamide)
T=20°C; 2 h;
参考文献
Nagato, Satoshi; Kawano, Koki; Ito, Koichi; Norimine, Yoshihiko; Ueno, Koshi; Hanada, Takahisa; Amino, Hiroyuki; Ogo, Makoto; Hatakeyama, Shinji; Ueno, Masataka; Groom, Anthony John; Rivers, Leanne; Smith, Terence
Patent: US2003/225081 A1, 2003 ;
Location in patent: Page 26 ;
US 20030225081 A1
