2-氨基-3-溴-4-甲基吡啶合成路线 （共 4 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; pentane T=-78°C; 1 h; 2: With sodium hydroxide; water in tetrahydrofuran; pentane pH=~ 12;
参考文献
AnorMED Inc.
Patent: US2005/277668 A1, 2005 ;
Location in patent: Page/Page column 28 ;
US 20050277668 A1
反应条件
hydrogen bromide; dihydrogen peroxide T=70°C; 1 h; Product distribution;
参考文献
Dunn, A. D.; Currie, A.; Hayes, L. E.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 3 p. 369 - 374
反应条件
1: With hydrogen bromide; bromine in water T=-10°C; 0.0833333 h; 2: With sodium nitrite in water T=0 - 10°C; 3.5 h; 3: With sodium hydroxide in water T=0°C; pH=~ 12;
参考文献
AnorMED Inc.
Patent: US2005/277668 A1, 2005 ;
Location in patent: Page/Page column 28 ;
US 20050277668 A1
反应条件
in N,N-dimethyl-formamide 20 h; Heating;
参考文献
Dunn; Norrie
Advanced Synthesis and Catalysis, 1996 , vol. 338, # 7 p. 663 - 666
