2,4,5,6-四氨基嘧啶盐酸盐合成路线 （共 7 条）
反应条件
BaCl2 in water T=85 - 90°C; 0.25 h;
参考文献
Kamen, Barton; Cole, Peter; Smith, Angela; Zebala, John A.
Patent: US2005/209239 A1, 2005 ;
Location in patent: Page/Page column 16 ;
反应条件
1: With sodium acetate; dl-cysteine hydrochloride in water T=20°C; 26 h; Heating / reflux; 2: With hydrogen bromide in ethanol T=70 - 75°C; 0.0833333 h; Heating / reflux;
参考文献
Kamen, Barton; Cole, Peter; Smith, Angela; Zebala, John A.
Patent: US2005/209239 A1, 2005 ;
Location in patent: Page/Page column 16 ;
反应条件
selenium(IV) oxide; sodium acetate in water
参考文献
Institutul Oncologic
Patent: US3989703 A1, 1976 ;
反应条件
in methanol Condensation; 2 h; Heating;
参考文献
Froehlich, Lothar G.; Kotsonis, Peter; Traub, Hermann; Taghavi-Moghadam, Shahriyar; Al-Masoudi, Najim; Hofmann, Heinrich; Strobel, Hartmut; Matter, Hans; Pfleiderer, Wolfgang; Schmidt, Harald H. H. W.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4108 - 4121
反应条件
in methanol Condensation; 2 h; Heating;
参考文献
Froehlich, Lothar G.; Kotsonis, Peter; Traub, Hermann; Taghavi-Moghadam, Shahriyar; Al-Masoudi, Najim; Hofmann, Heinrich; Strobel, Hartmut; Matter, Hans; Pfleiderer, Wolfgang; Schmidt, Harald H. H. W.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4108 - 4121
反应条件
in methanol
2 h; Heating;
参考文献
Taghavi-Moghadam, Shahriyar; Pfleiderer, Wolfgang
Tetrahedron Letters, 1997 , vol. 38, # 39 p. 6835 - 6836
反应条件
(i) MeOH, AcOH, H2O, (ii) NaOMe, (iii) H2O2; Multistep reaction;
参考文献
Weinstock,J. et al.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 3 p. 560 - 564
