3-氯-4-氨基三氟甲苯合成路线 （共 21 条）
反应条件
potassium fluoride; ammonia in 1-methyl-pyrrolidin-2-one T=245 - 250°C; P=22067.2 - 29422.9 Torr; 10 h; Autoclave;
参考文献
Gharda, Keki Hormusji
Patent: US2013/30190 A1, 2013 ;
Location in patent: Paragraph 0060 ;
反应条件
chlorine in chlorobenzene T=110°C; 6.5 h;
参考文献
BAYER CROPSCIENCE S.A.
Patent: WO2004/37766 A2, 2004 ;
Location in patent: Page 4 ;
反应条件
hydrogen; nickel in ethanol T=50°C; P=3750.38 Torr; 5 h;
参考文献
Aventis CropScience, S.A.
Patent: US6410737 B1, 2002 ;
Location in patent: Page column 8 ;
反应条件
potassium fluoride; ammonia in dimethylsulfone T=30 - 235°C; 6 h; Autoclave; Product distribution / selectivity;
参考文献
Gharda, Keki Hormusji
Patent: US2013/30190 A1, 2013 ;
Location in patent: Paragraph 0063 ;
参考文献
Aventis CropScience, S.A.
Patent: US6410737 B1, 2002 ;
Location in patent: Page column 6 ;
反应条件
2-picoline; Na2S2O5; sulfur dioxide; zinc in N,N-dimethyl-formamide T=50°C; P=2250.2 - 3750.3 Torr; 4 h;
参考文献
Tordeux, Marc; Langlois, Bernard; Wakselman, Claude
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 8 p. 2293 - 2299
反应条件
N-chloro-succinimide in acetonitrile 3 h; Heating;
参考文献
Nickson, Thomas E.; Roche-Dolson, Cathy A.
Synthesis, 1985 , # 6/7 p. 669 - 670
参考文献
Appel; Wolfgang; Siegemund; Gunter
Patent: US5471002 A1, 1995 ;
反应条件
sulfur dioxide; zinc in N,N-dimethyl-formamide P=2250.2 - 3750.3 Torr; 2 h; Ambient temperature;
参考文献
Wakselman, Claude; Tordeux, Marc
Journal of the Chemical Society, Chemical Communications, 1987 , p. 1701 - 1703
反应条件
sulfuric acid; dihydrogen peroxide; iron(II) sulfate in water; dimethyl sulfoxide
参考文献
Kino, Tatsuhito; Nagase, Yu; Ohtsuka, Yuhki; Yamamoto, Kyoko; Uraguchi, Daisuke; Tokuhisa, Kenji; Yamakawa, Tetsu
Journal of Fluorine Chemistry, 2010 , vol. 131, # 1 p. 98 - 105
