[2,3-联吡啶]-6-胺合成路线 （共 6 条）
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; acetonitrile
T=20 - 95°C; 24 - 48 h;
参考文献
METHYLGENE INC.
Patent: WO2005/92899 A1, 2005 ;
Location in patent: Page/Page column 55-56 ;
反应条件
SS-Phos; palladium diacetate; potassium carbonate in water
T=100°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Anderson, Kevin W.; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 38 p. 6173 - 6177
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=100°C; Stille Coupling; 16 h;
参考文献
Amrein, Kurt; Hunziker, Daniel; Kuhn, Bernd; Mayweg, Alexander; Neidhart, Werner
Patent: US2006/74237 A1, 2006 ;
Location in patent: Page/Page column 20 ;
反应条件
bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine; potassium carbonate in N,N-dimethyl acetamide; butan-1-ol
T=110°C; Suzuki Coupling; 24 h; Inert atmosphere;
参考文献
Wang, Kun; Fu, Qi; Zhou, Rong; Zheng, Xueli; Fu, Haiyan; Chen, Hua; Li, Ruixiang
Applied Organometallic Chemistry, 2013 , vol. 27, # 4 p. 232 - 238
反应条件
bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine; potassium carbonate in N,N-dimethyl acetamide; butan-1-ol
T=110°C; Suzuki Coupling; 20 h; Inert atmosphere;
参考文献
Wang, Kun; Fu, Qi; Zhou, Rong; Zheng, Xueli; Fu, Haiyan; Chen, Hua; Li, Ruixiang
Applied Organometallic Chemistry, 2013 , vol. 27, # 4 p. 232 - 238
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
12 h; Inert atmosphereReflux;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron, 2010 , vol. 66, # 17 p. 3135 - 3146
