2-氨基-6-溴吡啶

2-氨基-6-溴吡啶

6-bromopyridin-2-amine

19798-81-3

C5H5BrN2

173.01100

38.91000

2.00750

171.96400

略黄色至淡棕色粉末

118.9ºC

273ºC at 760 mmHg

88-91 °C(lit.)

1.71 g/cm3

0.0059mmHg at 25°C

GHS07

警告

H315; H319; H335

P261; P305 + P351 + P338

3

S26-S36-S36/37/39

Xn

R20/21/22; R36/37/38

2933399090

2933990090

2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

<p>在500mL三口瓶中加入冰醋酸300g,冰盐浴下通入干燥HBr约130g,制成约30%的溶液。然后在冰盐浴冷却下滴入25g(0.22mol)3-羟基戊二腈,需15~30min。加毕后继续搅拌25min,过滤,然后将固体加入200mL25%碳酸氢钠溶液中,搅拌15min,用乙醚100mL×3萃取,合并酸液,用20mL水洗涤后,无水硫酸钠干燥。回收乙醚后,固体用乙醚-石油醚(1∶1,v/v)重结晶。得产物约27g,收率71%。</p>

<p>用于有机合成</p>