alpha,beta-二氟-beta-氯苯乙烯合成路线 （共 12 条）
反应条件
1: 1.) NaNO2, aq. HCl / 1.) -10 to -15 deg C, 2.) H2O, acetone, 10-15 deg C, 2 h 2: 92 percent / Cu, pyridine / 2 h / 100 °C View Scheme
参考文献
Kremlev, M. M.; Maznyi, I. S.; Sereda, S. V.; Yagupol'skii, Yu. L.
Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 5.1 p. 758 - 761
Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 5 p. 982 - 986
参考文献
Meier; Boehler
Chemische Berichte, 1957 , vol. 90, p. 2342
反应条件
1: 71 percent / O2, Cl2 / 25 °C / Irradiation 2: 89 percent / 20percent aq. sodium bicarbonate / 0.5 h View Scheme
参考文献
Kremlev, M. M.; Maznyi, I. S.; Yagupol'skii, L. M.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 1.2 p. 105 - 108
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 1 p. 121 - 124
参考文献
Normant,J. et al.
Tetrahedron, 1975 , vol. 31, p. 891 - 896
反应条件
magnesium
1.) THF, 60 deg C, 2 h, 2.) 5 deg C; Yield given. Multistep reaction;
参考文献
Cherednichenko, P. G.; Kremlev, M. M.; Yagupol'skii, L. M.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. <l> 25, # 7.1 p. 1307 - 1311
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 7 p. 1451 - 1456
参考文献
Sauvetre,R.; Normant,J.-F.
Bulletin de la Societe Chimique de France, 1972 , p. 3202 - 3205
反应条件
iodine
1.) ether, THF, hexane, -70 to -65 deg C, 2 h; 2.) N-methylpyrrolidone, 120 deg C, 8 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Kremlev, M. M.; Moklyachuk, L. I.; Fialkov, Yu. A.; Yagupol'skii, L. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 814 - 817
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 5 p. 919 - 923
参考文献
Meier; Boehler
Chemische Berichte, 1957 , vol. 90, p. 2342
反应条件
oxygen; chlorine
T=25°C; Irradiation;
参考文献
Kremlev, M. M.; Maznyi, I. S.; Yagupol'skii, L. M.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 1.2 p. 105 - 108
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 1 p. 121 - 124
参考文献
Sauvetre, R.; Normant, J.F.
Tetrahedron Letters, 1982 , vol. 23, # 42 p. 4325 - 4328
