3,4-二甲氧基苯甲酸乙酯合成路线 （共 41 条）
反应条件
sodium hydroxide in water T=20°C; 6 h;
参考文献
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Patent: WO2006/40621 A1, 2006 ;
Location in patent: Page/Page column 15 ;
WO 2006/040621 A1
参考文献
Vela Pharmaceuticals, Inc.
Patent: US2004/152695 A1, 2004 ;
US 20040152695 A1
反应条件
1: With copper(l) iodide in chloroform T=20°C; 0.166667 h; 2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in chloroform 1 h; 3: With water in chloroform T=20°C; 12 h;
参考文献
Fu, Liang; Yao, Chang-Jiang; Chang, Ning-Jie; Chen, Jia-Rong; Lu, Liang-Qiu; Xiao, Wen-Jing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 506 - 508
反应条件
1: 3,4-dihydroxy-benzoic acid ethyl ester With potassium carbonate in acetone T=20°C; 0.5 h; 2: dimethyl sulfate T=50°C; 5 h;
参考文献
Liu, Yajing; Zhang, Shulan; Li, Ye; Wang, Jianqiang; Song, Yu; Gong, Ping
Archiv der Pharmazie, 2012 , vol. 345, # 4 p. 287 - 293
反应条件
sulfuric acid 3 h; Heating;
参考文献
Choshi; horimoto; Wang; Nagase; Ichikawa; Sugino; Hibino
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 4 p. 1047 - 1049
反应条件
dihydrogen peroxide; methyltrioxorhenium (VII) in ethanol T=50°C; 24 h;
参考文献
Yamazaki, Shigekazu
Chemistry Letters, 1995 , # 2 p. 127 - 128
反应条件
1: With sodium hydroxide 3 h; 2: T=20°C; 3 h;
参考文献
Verma, Alok K.; Singh, Himanshu; Satyanarayana, Mavurapu; Srivastava, Swayam P.; Tiwari, Priti; Singh, Amar B.; Dwivedi, Anil K.; Singh, Shio K.; Srivastava, Mukesh; Nath, Chandishwar; Raghubir, Ram; Srivastava, Arvind K.; Pratap, Ram
Journal of Medicinal Chemistry, 2012 , vol. 55, # 10 p. 4551 - 4567
反应条件
dihydrogen peroxide; methyltrioxorhenium (VII) T=50°C; 24 h;
参考文献
Yamazaki, Shigekazu
Chemistry Letters, 1995 , # 2 p. 127 - 128
反应条件
1.1: iodine / dichloromethane / 20 °C 2.1: copper(l) iodide / chloroform / 0.17 h / 20 °C 2.2: 1 h 2.3: 12 h / 20 °C View Scheme
参考文献
Fu, Liang; Yao, Chang-Jiang; Chang, Ning-Jie; Chen, Jia-Rong; Lu, Liang-Qiu; Xiao, Wen-Jing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 506 - 508
反应条件
potassium carbonate in butanone 84 h; Heating;
参考文献
Rowe, Kathryn E.; Bruce, Duncan W.
Journal of Materials Chemistry, 1998 , vol. 8, # 2 p. 331 - 341
