5-氨基-2-硝基三氟甲苯合成路线 （共 43 条）
反应条件
1: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuSO4 oder CuCl in wss. HCl in der Waerme 2: tin; aqueous hydrochloric acid View Scheme
参考文献
Whalley
Journal of the Chemical Society, 1949 , p. 3016,3019
反应条件
1: aqueous H2SO4; NaNO2 / Eintragen der erhaltenen Diazoniumsalz-Loesung in siedende wss. CuSO4-Loesung 2: tin; concentrated aqueous hydrochloric acid View Scheme
参考文献
Whalley
Journal of the Chemical Society, 1949 , p. 3016,3019
反应条件
1: ethanol; concentrated H2SO4 / 0 - 10 °C / Erwaermen der Reaktionsloesung mit Kupferbronze 2: palladium / Hydrogenation 3: Bildung ueber die Diazonium-Verbindung View Scheme
参考文献
Jones
Journal of the American Chemical Society, 1947 , vol. 69, p. 2352
反应条件
1: ethanol; concentrated H2SO4 / 0 - 10 °C / Erwaermen der Reaktionsloesung mit Kupferbronze 2: palladium / Hydrogenation 3: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr in wss. HBr View Scheme
参考文献
Jones
Journal of the American Chemical Society, 1947 , vol. 69, p. 2352
反应条件
thionyl chloride in N,N-dimethyl acetamide T=20°C;
参考文献
Steiner, Mitchell S.; Veverka, Karen A.; Miller, Duane D.
Patent: US2006/258628 A1, 2006 ;
Location in patent: Page/Page column 23 ;
反应条件
in N,N-dimethyl-aniline T=20°C;
参考文献
Gao, Mingzhang; Wang, Min; Miller, Kathy D.; Zheng, Qi-Huang
Steroids, 2011 , vol. 76, # 13 p. 1505 - 1512
反应条件
thionyl chloride in dimethylammonium 2,4-dichlorophenoxyacetate
参考文献
Dalton, James T.; Miller, Duane D.; Yin, Donghua; He, Yali
Patent: US2004/260108 A1, 2004 ;
反应条件
1: (i) H2SO4, EtNO2, EtOH, (ii) Cu 2: H2 / Raney-Ni / petroleum ether 3: (i) NaNO2, aq. HCl, (ii) NH3, SO2 View Scheme
参考文献
Forbes,E.J. et al.
Tetrahedron, 1960 , vol. 8, p. 67 - 72
反应条件
1: ethanol; concentrated H2SO4 / 0 - 10 °C / Erwaermen der Reaktionsloesung mit Kupferbronze 2: palladium / Hydrogenation 3: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuCl View Scheme
参考文献
Jones
Journal of the American Chemical Society, 1947 , vol. 69, p. 2352
反应条件
1: acetic acid; sulfuric acid; aqueous sodium nitrite solution / Reagens 4: wss. Phosphinsaeure 2: Raney nickel; dioxane / 180 °C / 14710.2 Torr / Hydrogenation View Scheme
参考文献
Jones
Journal of the American Chemical Society, 1947 , vol. 69, p. 2352
