1,1-二苯基-2-丙炔-1-醇合成路线 （共 64 条）
参考文献
Kodama, Yoichi; Nakabayashi, Takakazu; Segawa, Katsunori; Hattori, Emi; Sakuragl, Masako; Nlshi, Nobuyuki; Sakuragi, Hirochika
Journal of Physical Chemistry A, 2000 , vol. 104, # 49 p. 11478 - 11485
反应条件
pyridine; thionyl chloride in diethyl ether
参考文献
Nagase,T.
Bulletin of the Chemical Society of Japan, 1961 , vol. 34, # 1 p. 139 - 140
反应条件
dicobalt octacarbonyl; dimethylsulfide borane complex; water; trifluoroacetic acid
Yield given. Multistep reaction;
参考文献
McComsey, David F.; Reitz, Allen B.; Maryanoff, Cynthia A.; Maryanoff, Bruce E.
Synthetic Communications, 1986 , vol. 16, # 12 p. 1535 - 1550
反应条件
1: 1.) Hg(OAc)2, 2.) thioacetamide / 1.) 72 h, 2.) 3 h
2: aq. KOH / methanol / 0.25 h / Heating
View Scheme
参考文献
Carter; Noronha-Blob; Audia; Dupont; McPherson; Natalie Jr.; Rzeszotarski; Spagnuolo; Waid; Kaiser
Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3065 - 3074
反应条件
1: Et3N / CHCl3
2: toluene / Heating
View Scheme
参考文献
Kato; Chiba
Chemical and Pharmaceutical Bulletin, 1975 , vol. 23, # 10 p. 2263 - 2267
反应条件
trifluoroacetic acid; [Ru(η3-2-C3H4Me)(CO)(1,1'-(Ph2P)2-ferrocene)][SbF6]
T=75°C; 2 h; sealed tube;
参考文献
Cadierno, Victorio; Diez, Josefina; Garcia-Garrido, Sergio E.; Gimeno, Jose; Nebra, Noel
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2125 - 2132
反应条件
sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
Clavier, Herve; Nolan, Steven P.
Chemistry - A European Journal, 2007 , vol. 13, # 28 p. 8029 - 8036
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 1 h / -78 °C
2.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 80 °C
View Scheme
参考文献
Mothe, Srinivasa Reddy; Lauw, Sherman Jun Liang; Kothandaraman, Prasath; Chan, Philip Wai Hong
Journal of Organic Chemistry, 2012 , vol. 77, # 16 p. 6937 - 6947
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 1 h / -78 °C
2.1: toluene-4-sulfonic acid / dichloromethane / 0.5 h / 80 °C
View Scheme
参考文献
Mothe, Srinivasa Reddy; Lauw, Sherman Jun Liang; Kothandaraman, Prasath; Chan, Philip Wai Hong
Journal of Organic Chemistry, 2012 , vol. 77, # 16 p. 6937 - 6947
参考文献
Sacharkin
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1956 , p. 313,320; engl. Ausg. S. 303, 309
Full Text Show Details
Heilmann; Glenat
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1955 , vol. 240, p. 877
Bulletin de la Societe Chimique de France, 1955 , p. 1586,1590
