1,1-二苯基-2-丙炔-1-醇合成路线 （共 64 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-10°C; 4 h; Inert atmosphere; 2: With sodium hydroxide in methanol T=0°C;
参考文献
Mondon, Martine; Delatouche, Regis; Bachmann, Christian; Frapper, Gilles; Len, Christophe; Bertrand, Philippe
European Journal of Organic Chemistry, 2011 , # 11 p. 2111 - 2119
反应条件
in tetrahydrofuran; xylene T=-10 - 20°C;
参考文献
Teral, Yannick; Roubaud, Gabriel; Aubert, Claude; Faure, Robert; Campredon, Mylene
Australian Journal of Chemistry, 2005 , vol. 58, # 7 p. 517 - 521
反应条件
potassium carbonate in methanol T=20°C; 2 h; Inert atmosphere;
参考文献
Maraval, Valerie; Duhayon, Carine; Coppel, Yannick; Chauvin, Remi
European Journal of Organic Chemistry, 2008 , # 30 p. 5144 - 5156
反应条件
in tetrahydrofuran T=-78 - 20°C; 20 h; Inert atmosphere;
参考文献
Zhang, Huan; Tanimoto, Hiroki; Morimoto, Tsumoru; Nishiyama, Yasuhiro; Kakiuchi, Kiyomi
Organic Letters, 2013 , vol. 15, # 20 p. 5222 - 5225
反应条件
1: acetylene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: benzophenone in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Kuwatani, Yoshiyuki; Yamamoto, Gaku; Oda, Masaji; Iyoda, Masahiko
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 12 p. 2188 - 2208
反应条件
1: in tetrahydrofuran T=-78 - -20°C; 2: With water; ammonium chloride in tetrahydrofuran
参考文献
Arai, Shigeru; Sato, Takashi; Koike, Yuka; Hayashi, Michino; Nishida, Atsushi
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 4528 - 4531
Angewandte Chemie, 2009 , vol. 121, p. 4598 - 4601
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=0°C; 3 h;
参考文献
Nishimura, Takahiro; Guo, Xun-Xiang; Ohnishi, Kohei; Hayashi, Tamio
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2669 - 2672
反应条件
acetylene in N,N-dimethyl acetamide T=25°C; 1.75 h;
参考文献
Beumel,O.F.; Harris,R.F.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1872 - 1876
参考文献
Harie, Guenaelle; Samat, Andre; Guglielmetti, Robert; De Keukeleire, Denis; Saeyens, Wim; Van Parys, Inge
Tetrahedron Letters, 1997 , vol. 38, # 17 p. 3075 - 3078
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -70 °C / Inert atmosphere 1.2: 1 h / -70 - 20 °C / Inert atmosphere 2.1: methanol; potassium carbonate / 2 h / 20 °C View Scheme
参考文献
Saalfrank, Rolf W.; Welch, Andreas; Haubner, Martin; Bauer, Udo
Liebigs Annales, 1996 , # 2 p. 171 - 181
