二(2-溴乙基)胺合成路线

参考文献

Zhou, Xinbo; Chen, Wei; Xu, Cheng; Fan, Shiyong; Xie, Yunde; Zhong, Wu; Wang, Lili; Li, Song
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 8 p. 2605 - 2608

5338-18-1N,N-二[2-(乙酰氧基)乙基]-乙酰胺

3890-99-1二(2-溴乙基)胺

参考文献

Mann
Journal of the Chemical Society, 1934 , p. 464

182805-17-0

3890-99-1二(2-溴乙基)胺

参考文献

Gabriel; Eschenbach
Chemische Berichte, 1897 , vol. 30, p. 810

25114-70-92,2,2-次氮基三乙醇氢溴酸盐

3890-99-1二(2-溴乙基)胺

参考文献

Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 484

182805-17-0+

10035-10-6氢溴酸

3890-99-1二(2-溴乙基)胺

参考文献

Gabriel; Eschenbach
Chemische Berichte, 1897 , vol. 30, p. 810

10035-10-6氢溴酸+

25114-70-92,2,2-次氮基三乙醇氢溴酸盐

89583-07-32-(4-吗啉)乙基溴+

3890-99-1二(2-溴乙基)胺

参考文献

Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 484

3890-99-1二(2-溴乙基)胺+

95-54-51,2-苯二胺

13339-02-12-(1-哌嗪)苯胺

参考文献

Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218

3890-99-1二(2-溴乙基)胺+

24424-99-5二碳酸二叔丁酯

159635-50-4N-Boc-N,N-双(2-溴乙基)胺

参考文献

Yang, Lihu; Morriello, Greg; Prendergast, Kristine; Cheng, Kang; Jacks, Tom; Chan, Wanda W.-S.; Schleim, Klaus D.; Smith, Roy G.; Patchett, Arthur A.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 1 p. 107 - 112

3890-99-1二(2-溴乙基)胺

122413-80-3

参考文献

Cher, Chen Ben; Pantev, T. P.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 6 p. 503 - 505
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 6 p. 708 - 709

3890-99-1二(2-溴乙基)胺+

541-41-3氯甲酸乙酯

77697-11-1双(2-溴乙基)氨基甲酸乙酯

参考文献

NOVARTIS AG; CHEN, Zhuoliang; CHEUNG, Atwood, Kim; CHIN, Donovan, Noel; FAN, Jianmei; MILLER-MOSLIN, Karen, Marie; SHULTZ, Michael, David; SMITH, Troy, D.; TOMLINSON, Ronald, Charles; TOURE, Bakary-Barry; VISSER, Michael, Scott
Patent: WO2013/12723 A1, 2013 ;
Location in patent: Page/Page column 59 ;
WO 2013/012723 A1