2,5-二甲氧基苯-1,4-二乙腈合成路线 （共 9 条）
反应条件
hydrogenchloride; bromine; lithium diisopropyl amide 1.) benzene, 0-5 deg C, 4 h; 2.) water, 20 deg C, 48 h; Yield given. Multistep reaction;
参考文献
Bryce, Martin R.; Hasan, Masihul; Ashwell, Geoffrey J.
Journal of the Chemical Society, Chemical Communications, 1989 , # 9 p. 529 - 530
参考文献
Jacini; Bacchetti
Gazzetta Chimica Italiana, 1950 , vol. 80, p. 757,760
反应条件
1: aqueous formaldehyde; dioxane; HCl; concentrated aqueous HCl / 20 °C
2: acetone; 1-ethoxy-ethanol-(2)
View Scheme
参考文献
Wood; Gibson
Journal of the American Chemical Society, 1949 , vol. 71, p. 393
反应条件
1-ethoxyethanol; acetone
参考文献
Wood; Gibson
Journal of the American Chemical Society, 1949 , vol. 71, p. 393
反应条件
in dimethyl sulfoxide
T=50 - 85°C;
参考文献
Liao, Jian; Wang, Qing
Macromolecules, 2004 , vol. 37, # 18 p. 7061 - 7063
反应条件
in dimethyl sulfoxide
参考文献
Sakamoto,K.; Oki,M.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 497 - 504
Full Text Show Details
Wheland,R.S.; Martin,E.L.
Journal of Organic Chemistry, 1975 , vol. 40, # 21 p. 3101 - 3109
反应条件
2: SOCl2 / diethyl ether
View Scheme
参考文献
Sakamoto,K.; Oki,M.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 497 - 504
参考文献
Nakao,H.; Arakawa,M.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1962 - 1967
反应条件
1: (i) KOH, (ii) /BRN= 1718733/, H2SO4
2: HNO3 / acetic acid
View Scheme
参考文献
Schill,G.
Justus Liebigs Annalen der Chemie, 1966 , vol. 691, p. 79 - 87
