3,4,5-三甲氧基苄醇合成路线 （共 102 条）
反应条件
potassium phosphate; copper quinolate; tetra-(n-butyl)ammonium iodide in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
1: LiBr, TMSCl / acetonitrile 2: toluene 3: n-BuLi / tetrahydrofuran 4: (n-Bu)4NF / tetrahydrofuran View Scheme
参考文献
Guo, Xiaotao; Zhang, Dan; Yu, Zhifang; Liu, Tianzhen; Li, Dachang; Li, Chunbao
Journal of Chemical Research, 2011 , vol. 35, # 4 p. 229 - 230
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=0°C; Wittig type reaction; 2: 3,4,5-trimethoxy-benzyl alcohol With 4,4'-di-tert-butylbiphenyl; lithium; nickel dichloride in tetrahydrofuran; hexane Wittig type reaction; 48 h; Inert atmosphereReflux;
参考文献
Alonso, Francisco; Riente, Paola; Yus, Miguel
European Journal of Organic Chemistry, 2009 , # 34 p. 6034 - 6042
反应条件
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane 2: n-butyllithium / tetrahydrofuran View Scheme
参考文献
Ishi-I, Tsutomu; Sakai, Miki; Shinoda, Chihiro
Tetrahedron, 2013 , vol. 69, # 45 p. 9475 - 9480
反应条件
1: N.N-dimethyl-aniline; SOCl2 / 0 °C / zuletzt bei 100grad 2: ethanol 3: Hydrolysis.Decarboxylierung View Scheme
参考文献
Cook et al.
Journal of the Chemical Society, 1944 , p. 322,324
反应条件
[2,2']bipyridinyl; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; copper(l) chloride in neat (no solvent)
T=20°C; 13 h; Green chemistry;
参考文献
Yu, Jiatao; Xu, Jian; Lu, Ming
Applied Organometallic Chemistry, 2013 , vol. 27, # 10 p. 606 - 610
反应条件
in dichloromethane
T=25°C; 0.333333 h; reaction with other alcohols; Product distribution;
参考文献
Dess, D. B.; Martin, J. C.
Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4155 - 4156
反应条件
1: LiBr, TMSCl / acetonitrile
2: toluene
3: n-BuLi / tetrahydrofuran
4: (n-Bu)4NF / tetrahydrofuran
6: MCPBA
View Scheme
参考文献
Bedford, Simon B.; Quarterman, Charmaine P.; Rathbone, Daniel L.; Slack, John A.; Griffin, Roger J.; Stevens, Malcolm F. G.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 2 p. 157 - 160
反应条件
1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 20 °C
2: 30 percent / AlCl3 / CH2Cl2 / 12 h / 20 °C
3: 75 percent / triethylamine / 2 h / 20 °C
View Scheme
参考文献
Zou, Hong Bin; Dong, Sheng Yi; Zhou, Chang Xin; Hu, Li Hong; Wu, Yi Hang; Li, Hai Bo; Gong, Jing Xu; Sun, Lian Li; Wu, Xiu Mei; Bai, Hua; Fan, Bo Tao; Hao, Xiao Jiang; Stoeckigt, Joachim; Zhao, Yu
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2060 - 2071
反应条件
1: 98 percent / iodine, silver trifluoroacetate / CH2Cl2 / 4 h
2: 93 percent / pyridinium dichromate / CH2Cl2 / 12 h / Ambient temperature
View Scheme
参考文献
Larson, Eric R.; Raphael, Ralph A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 521 - 525
