(2-溴苯基乙炔基)三甲基硅烷合成路线 （共 32 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine T=20°C; Inert atmosphere;
参考文献
Ishida, Tomonobu; Kikuchi, Satoshi; Tsubo, Tatsuyuki; Yamada, Tohru
Organic Letters, 2013 , vol. 15, # 4 p. 848 - 851
反应条件
triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) Heating;
参考文献
Grubbs, Robert H.; Kratz, Detlef
Chemische Berichte, 1993 , vol. 126, # 1 p. 149 - 158
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in triethylamine T=70°C; 7 h;
参考文献
Huynh, Chanh; Linstrumelle, Gerard
Tetrahedron, 1988 , vol. 44, # 20 p. 6337 - 6344
反应条件
(i) EtMgBr, Et2O, (ii) /BRN= 1209232/; Multistep reaction;
参考文献
Evans,A.G. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1974 , p. 1216 - 1219
反应条件
1: Pd(0) / methanol 2: K2CO3 / methanol View Scheme
参考文献
John, Jens A.; Tour, James M.
Journal of the American Chemical Society, 1994 , vol. 116, # 11 p. 5011 - 5012
反应条件
1: 1.) tert-BuLi, 2.) Te / 1) ether, pentane, -80 deg C, 1 h, -80 to -30 deg C, 1 h; 2) ether, pentane, rt, 1-2 h 2: 74 percent / NaBH4 / ethanol / 12 h / 80 °C View Scheme
参考文献
Kurita; Ishii; Yasuike; Tsuchiya
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 7 p. 1437 - 1441
反应条件
Na2S*9H2O in 1-methyl-pyrrolidin-2-one T=185 - 195°C; 12 h; Inert atmosphere;
参考文献
Kashiki, Tomoya; Shinamura, Shoji; Kohara, Masahiro; Miyazaki, Eigo; Takimiya, Kazuo; Ikeda, Masaaki; Kuwabara, Hirokazu
Organic Letters, 2009 , vol. 11, # 11 p. 2473 - 2475
反应条件
selenium; sodium tetrahydroborate in 1-methyl-pyrrolidin-2-one T=190°C; 12 h; Inert atmosphere;
参考文献
Kashiki, Tomoya; Shinamura, Shoji; Kohara, Masahiro; Miyazaki, Eigo; Takimiya, Kazuo; Ikeda, Masaaki; Kuwabara, Hirokazu
Organic Letters, 2009 , vol. 11, # 11 p. 2473 - 2475
反应条件
methanol; potassium carbonate in tetrahydrofuran T=20°C;
参考文献
Alabugin, Igor V.; Gilmore, Kerry; Patil, Satish; Manoharan, Mariappan; Kovalenko, Serguei V.; Clark, Ronald J.; Ghiviriga, Ion
Journal of the American Chemical Society, 2008 , vol. 130, # 34 p. 11535 - 11545
反应条件
1.1: 96 percent / K2CO3 / methanol; CH2Cl2 / 0.5 h / 25 °C 2.1: LDA / tetrahydrofuran / 0.33 h / -78 °C 2.2: 85 percent / tetrahydrofuran / -78 - 25 °C 3.1: 92 percent / PdCl2(PhCN)2; CuI; NH(i-Pr)2 / P(t-Bu)3 / tetrahydrofuran 4.1: 95 percent / K2CO3 / methanol; CH2Cl2 / 0.5 h / 25 °C 5.1: 71 percent / H2O; [tris(1-pyrazolyl)borate]RuPPh3(CH3CN)2PF6 / various solvent(s) / 24 h / 100 °C View Scheme
参考文献
Odedra, Arjan; Wu, Chang-Jung; Pratap, Taduri Bhanu; Huang, Chun-Wei; Ran, Ying-Fen; Liu, Rai-Shung
Journal of the American Chemical Society, 2005 , vol. 127, # 10 p. 3406 - 3412
