2,4,6-三氯嘧啶合成路线

参考文献

Ramesh, A.; Sundar, B. Syama; Murti, P. S. Radhakrishna
Journal of the Indian Chemical Society, 1995 , vol. 72, # 6 p. 413 - 416

3764-01-02,4,6-三氯嘧啶+

64-17-5乙醇+

74-89-5甲胺

10397-15-64,6-二氯-N-甲基嘧啶-2-胺+

32998-03-12,6-二氯-n-甲基-4-嘧啶胺

参考文献

Winkelmann
Journal fuer Praktische Chemie (Leipzig), 1927 , vol. <2> 115, p. 293

67-56-1甲醇+

3764-01-02,4,6-三氯嘧啶

43212-41-52,4-二氯-6-甲氧基嘧啶+

1074-40-44,6-二氯-2-甲氧基嘧啶

参考文献

Kumar, C.H. Vinod; Kavitake, Santosh; Kumar, Sythana Suresh; Cornwall, Philip; Ashok, Mithun; Bhagat, Sagar; Manjunatha, Sulur G.; Nambiar, Sudhir
Organic Process Research and Development, 2012 , vol. 16, # 8 p. 1416 - 1421

110-91-8吗啉+

3764-01-02,4,6-三氯嘧啶

10244-24-32,4-双(4-吗啉基)-6-氯嘧啶

参考文献

NOVARTIS AG; CALIENNI, John Vincent; DE LA CRUZ, Marilyn; FLUBACHER, Dietmar; GONG, Baoqing; KAPA, Prasad Koteswara; KARPINSKI, Piotr H.; LIU, Hui; MICHEL, Pascal; MOSE, Rasmus; TESTA, Maria Caterina; WAYKOLE, Liladhar Murlidhar
Patent: WO2012/44727 A2, 2012 ;
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110-91-8吗啉+

3764-01-02,4,6-三氯嘧啶

10244-24-32,4-双(4-吗啉基)-6-氯嘧啶+

52127-83-04-(2,6-二氯-4-嘧啶)吗啉+

479493-68-0

参考文献

WO2008/98058 A1, ;

Page/Page column 57-58 ;
WO 2008/098058 A1

3764-01-02,4,6-三氯嘧啶

10244-24-32,4-双(4-吗啉基)-6-氯嘧啶+

479493-68-0

参考文献

ACS Medicinal Chemistry Letters, , vol. 2, # 10 p. 774 - 779

110-91-8吗啉+

3764-01-02,4,6-三氯嘧啶

10244-24-32,4-双(4-吗啉基)-6-氯嘧啶+

479493-68-0

参考文献

NOVARTIS AG
Patent: WO2007/84786 A1, 2007 ;
Location in patent: Page/Page column 123 ;
WO 2007/084786 A1

3764-01-02,4,6-三氯嘧啶

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234
Full Text Show Details
Gabriel; Colman
Chemische Berichte, 1903 , vol. 36, p. 3383

3764-01-02,4,6-三氯嘧啶+

124-41-4甲醇钠

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

Ioannidis, Stephanos; Lamb, Michelle L.; Almeida, Lynsie; Guan, Huiping; Peng, Bo; Bebernitz, Geraldine; Bell, Kirsten; Alimzhanov, Marat; Zinda, Michael
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1669 - 1673

67-56-1甲醇+

3764-01-02,4,6-三氯嘧啶+

124-41-4甲醇钠

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/135786 A1, 2008 ;
Location in patent: Page/Page column 57-58 ;
WO 2008/135786 A1