3-(3,4-二甲氧基苯基)-1(3H)-异苯并呋喃酮合成路线 （共 9 条）
反应条件
1: 2-Bromobenzoic acid With Di-n-butylmagnesium in tetrahydrofuran
2: With n-butyllithium in tetrahydrofuran
T=-20°C; 1 h;
3: 3,4-dimethoxy-benzaldehyde in tetrahydrofuran
T=-20°C; 1 h;
参考文献
Amaladass, Pitchamuthu; Clement, J. Arul; Mohanakrishnan, Arasambattu K.
European Journal of Organic Chemistry, 2008 , # 22 p. 3798 - 3810
反应条件
trifluoroacetic acid
0.25 h; Heating;
参考文献
Godbole, Himanshu M.; Joseph, Augustine R.
Journal of Chemical Research, Synopses, 1998 , # 6 p. 332 - 333
反应条件
perchloric acid
T=100°C; 1.5 h;
参考文献
Barili, Pier Luigi; Scartoni, Valerio
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1199 - 1202
反应条件
1: 2-Iodo-benzoic acid ethyl ester With iso-propylmagnesium bromide
T=-40°C; 1 h;
2: 3,4-dimethoxy-benzaldehyde T=-40 - 20°C; 1 h;
参考文献
Mohanakrishnan, Arasambattu K.; Amaladass
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4225 - 4229
反应条件
potassium carbonate; α-bromoacetophenone in butanone
Cycloaddition; 11 h; Heating;
参考文献
Purohit; Mukherjee
Journal of the Indian Chemical Society, 1998 , vol. 75, # 5 p. 310 - 312
反应条件
1: BuLi
2: aq. H2SO4
3: Na2Cr2O7
View Scheme
参考文献
Kobayashi, Kazuhiro; Maeda, Kouji; Uneda, Tomokazu; Morikawa, Osamu; Konishi, Hisatoshi
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 4 p. 443 - 446
反应条件
1: BuLi
2: aq. H2SO4
3: Na2Cr2O7
View Scheme
参考文献
Kobayashi, Kazuhiro; Maeda, Kouji; Uneda, Tomokazu; Morikawa, Osamu; Konishi, Hisatoshi
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 4 p. 443 - 446
反应条件
1: aq. H2SO4
2: Na2Cr2O7
View Scheme
参考文献
Kobayashi, Kazuhiro; Maeda, Kouji; Uneda, Tomokazu; Morikawa, Osamu; Konishi, Hisatoshi
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 4 p. 443 - 446
反应条件
potassium hydroxide
Oxydation des Reaktionsprodukts mit Permanganat;
参考文献
Bistrzycki; Zen-Ruffinen
Helvetica Chimica Acta, 1920 , vol. 3, p. 373
