(5-甲氧基-1-苯并呋喃-2-基)甲醇合成路线 （共 9 条）
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane 1 h;
参考文献
BIOLIPOX AB
Patent: WO2008/110793 A1, 2008 ;
Location in patent: Page/Page column 110 ;
反应条件
manganese(IV) oxide in ethyl acetate T=20°C; 26 h;
参考文献
SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2005/68460 A1, 2005 ;
Location in patent: Page/Page column 313 ;
WO 2005/068460 A1
反应条件
diisobutylaluminium hydride in tetrahydrofuran
T=-78 - 20°C; 4.33333 h;
参考文献
SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2005/68460 A1, 2005 ;
Location in patent: Page/Page column 313 ;
WO 2005/068460 A1
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
T=0°C;
2: With sodium hydrogencarbonate in water
参考文献
Korea Institute of Science and Technology; HANMI HOLDINGS CO., LTD
Patent: US2011/124888 A1, 2011 ;
Location in patent: Page/Page column 6 ;
反应条件
sodium tetrahydroborate in ethanol; chloroform
T=30 - 40°C; 1 h;
参考文献
Mukhanova; Kukushkin; Ivanov; Alekseeva; Granik
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 325 - 329
反应条件
sulfuric acid; water in ethylene glycol dimethyl ether
T=40°C; 15 h; Inert atmosphere;
参考文献
Gabriele, Bartolo; Mancuso, Raffaella; Salerno, Giuseppe
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7336 - 7341
反应条件
ammonium chloride; diisobutylaluminium hydride in tetrahydrofuran; hexane; ethyl acetate
参考文献
Merck Frosst Canada, Inc.
Patent: US5091533 A1, 1992 ;
反应条件
1: 90 percent / NaBH4 / ethanol; CHCl3 / 1 h / 30 - 40 °C
View Scheme
参考文献
Mukhanova; Kukushkin; Ivanov; Alekseeva; Granik
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 325 - 329
反应条件
in water; acetone; acetonitrile
Sonogashira reaction; 24 h; Inert atmospherePhotolysis;
参考文献
Protti, Stefano; Fagnoni, Maurizio; Albini, Angelo
Journal of Organic Chemistry, 2012 , vol. 77, # 15 p. 6473 - 6479
