(1-甲基-1H-吡咯-2-基)苯基甲酮合成路线 （共 17 条）
反应条件
oxalyl dichloride in dichloromethane; N,N-dimethyl-formamide T=20°C; Vilsmeier-Haack reaction; 1 h;
参考文献
Ragno, Rino; Mai, Antonello; Massa, Silvio; Cerbara, Ilaria; Valente, Sergio; Bottoni, Patrizia; Scatena, Roberto; Jesacher, Florian; Loidl, Peter; Brosch, Gerald
Journal of Medicinal Chemistry, 2004 , vol. 47, # 6 p. 1351 - 1359
反应条件
aluminium trichloride in dichloromethane 0.25 h;
参考文献
Lehr, Matthias
Journal of Medicinal Chemistry, 1997 , vol. 40, # 21 p. 3381 - 3392
反应条件
zinc trifluoromethanesulfonate in nitromethane
T=20°C; Friedel-Crafts acylation; 8 h;
参考文献
He, Fei; Wu, Huayue; Chen, Jiuxi; Su, Weike
Synthetic Communications, 2008 , vol. 38, # 2 p. 255 - 264
反应条件
tetrafluoroboric acid; mercury(II) oxide in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Barbero, Margherita; Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Regondi, Valeria
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2245 - 2250
反应条件
1: N,N-dimethyl benzamide With bis(trichloromethyl) carbonate in tetrachloromethane
T=0°C;
2: 1-methyl-pyrrole in tetrachloromethane
T=40 - 50°C; Vilsmeier-Haack reaction; 1 h;
3: With sodium hydroxide in tetrachloromethane
参考文献
Shi; Su; Shan
Journal of the Indian Chemical Society, 2005 , vol. 82, # 11 p. 1019 - 1021
反应条件
in tetrahydrofuran; hexane
T=0°C; 1.5 h;
参考文献
Brittain, Judith M.; Jones, R. Alan; Arques, Jose Sepulveda; Saliente, Teresa Aznar
Synthetic Communications, 1982 , vol. 12, # 3 p. 231 - 248
反应条件
1-butylpyridinium tetrafluoroborate; ytterbium(III) triflate
T=20°C; Friedel-Crafts reaction; 2 h;
参考文献
Su, Weike; Wu, Chunlei; Su, Hao
Journal of Chemical Research, 2005 , # 1 p. 67 - 68
反应条件
in tetrahydrofuran; hexane
T=0°C; 1.5 h;
参考文献
Brittain, Judith M.; Jones, R. Alan; Arques, Jose Sepulveda; Saliente, Teresa Aznar
Synthetic Communications, 1982 , vol. 12, # 3 p. 231 - 248
反应条件
1: 40 percent / pyridine / acetonitrile / 1 h / Ambient temperature
2: 92 percent / HgO, aq. HBF4 / tetrahydrofuran / 0.5 h / Ambient temperature
View Scheme
参考文献
Barbero, Margherita; Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Regondi, Valeria
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2245 - 2250
反应条件
1: 40 percent / pyridine / acetonitrile / 1 h / Ambient temperature
2: 92 percent / HgO, aq. HBF4 / tetrahydrofuran / 0.5 h / Ambient temperature
View Scheme
参考文献
Barbero, Margherita; Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Regondi, Valeria
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2245 - 2250
