解草啶合成路线 - 魔法化学

参考文献

Castelhano, Arlindo; McKibben, Bryan; Steinig, Arno; Collington, Eric
Patent: US2003/162764 A1, 2003 ;
US 20030162764 A1

1193-21-14,6-二氯嘧啶+

108-86-1溴代苯

3740-92-9解草啶

参考文献

MIIKANA THERAPEUTICS, INC.
Patent: WO2008/154026 A1, 2008 ;
Location in patent: Page/Page column 88 ;
WO 2008/154026 A1

591-51-5苯基锂

3740-92-9解草啶

参考文献

Harden, Donald B.; Mokrosz, Maria J.; Strekowski, Lucjan
Journal of Organic Chemistry, 1988 , vol. 53, # 17 p. 4137 - 4140

56-05-32-氨基-4,6-二氯嘧啶+

71-43-2苯

3740-92-9解草啶

参考文献

Lee, Hong Woo; Bok, Young Kim; Joong, Bok Ahn; Sung, Kwon Kang; Lee, Jung Hwa; Jae, Soo Shin; Soon, Kil Ahn; Lee, Sang Joon; Seung, Soo Yoon
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 9 p. 862 - 874

1670-14-0苄脒盐酸盐

3740-92-9解草啶

参考文献

Biagi; Giorgi; Livi; Scartoni; Lucacchini
Farmaco, 1997 , vol. 52, # 1 p. 61 - 65

63447-35-82-苯基-4,6-嘧啶二醇+

121-69-7N,N-二甲基苯胺

3740-92-9解草啶

参考文献

Hendry; Homer
Journal of the Chemical Society, 1952 , p. 328,333

3740-92-9解草啶+

124-40-3二甲胺

58514-86-6N-(6-氯-2-苯基-4-嘧啶)-N,N-二甲基胺

参考文献

TAISHO PHARMACEUTICAL CO., LTD.; Arena Pharmaceuticals, Inc
Patent: WO2005/95357 A2, 2005 ;
Location in patent: Page/Page column 171 ;
WO 2005/095357 A2

3740-92-9解草啶+

75-04-7乙胺

289-95-2嘧啶

参考文献

Ciba-Geigy Corporation
Patent: US4962191 A1, 1990 ;

3740-92-9解草啶+

105-13-5茴香醇

1044559-74-1

参考文献

WO2008/95999 A1, ;

Page/Page column 74 ;

3740-92-9解草啶

26871-14-7N-(6-氯-2-苯基-4-嘧啶)-n-乙胺