反应条件
1: N,N,N',N,-tetramethylethylenediamine; n-butyllithium / diethyl ether
2: ammonium hydroxide / methanol
3: sodium hydroxide / N,N-dimethyl acetamide / 1 h / 10 - 20 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Xu, Yuelian; Han, Bingsong; Wang, Zhe-Qing; Shaw, Kenneth R.; Chenard, Bertrand L.; Maynard, George; Xie, Linghong
Organic Process Research and Development, 2007 , vol. 11, # 4 p. 716 - 720