2-(1-金刚烷氨基)乙醇合成路线 （共 6 条）
反应条件
1: in benzonitrile
T=120°C; 12 h;
2: With sodium carbonate in dichloromethane
参考文献
BASF SE; BASF (CHINA) COMPANY LIMITED; HASHMI, A., Stephen K.; LOTHSCHUeTZ, Christian
Patent: WO2012/56419 A1, 2012 ;
Location in patent: Page/Page column 67 ;
反应条件
in ethanol
T=60 - 70°C; 4 h; in an autoclave;
参考文献
Plakhotnik, V. M.; Kovtun, V. Yu.; Krasutskii, P. A.; Novikova, M. I.; Prokhorov, A. B.; et al.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1287 - 1290
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1447 - 1450
反应条件
palladium on activated charcoal
参考文献
Plakhotnik, V. M.; Kovtun, V. Yu.; Krasutskii, P. A.; Novikova, M. I.; Prokhorov, A. B.; et al.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1287 - 1290
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1447 - 1450
反应条件
in tetrahydrofuran; water
参考文献
Aldrich; Hermann; Meier; Paulshock; Prichard; Snyder; Watts
Journal of medicinal chemistry, 1971 , vol. 14, # 6 p. 535 - 543
反应条件
1: 70 percent / 10percent Pd/C
View Scheme
参考文献
Plakhotnik, V. M.; Kovtun, V. Yu.; Krasutskii, P. A.; Novikova, M. I.; Prokhorov, A. B.; et al.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1287 - 1290
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1447 - 1450
反应条件
triethylamine
T=120°C; 3 h; with/without Et3N; other temperature; Product distribution;
参考文献
Plakhotnik, V. M.; Kovtun, V. Yu.; Krasutskii, P. A.; Novikova, M. I.; Prokhorov, A. B.; et al.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1287 - 1290
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1447 - 1450
