(4-氟苯基)(甲基氨基)乙腈合成路线 （共 4 条）
反应条件
acetic acid in methanol
T=0 - 20°C; 18 h; Inert atmosphere;
参考文献
Emsermann, Jens; Arduengo, Anthonyj.; Opatz, Till
Synthesis (Germany), 2013 , vol. 45, # 16 art. no. SS-2013-T0283-OP, p. 2251 - 2264
反应条件
1: 4-fluorobenzaldehyde; methylamine in methanol; water
Strecker amino acid synthesis; 1 h;
2: trimethylsilyl cyanide in methanol; water
T=20°C; Strecker amino acid synthesis;
参考文献
Vongvilai, Pornrapee; Linder, Mats; Sakulsombat, Morakot; Svedendahl Humble, Maria; Berglund, Per; Brinck, Tore; Ramstroem, Olof
Angewandte Chemie - International Edition, 2011 , vol. 50, # 29 p. 6592 - 6595
反应条件
in methanol; water
T=20°C; 4 h;
参考文献
Cantillo, David; Avalos, Martin; Babiano, Reyes; Cintas, Pedro; Jimenez, Jose L.; Light, Mark E.; Palacios, Juan C.; Rodriguez, Valentin
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 23 p. 5367 - 5374
反应条件
in acetonitrile
20 h;
参考文献
Weinhardt; Beard; Dvorak; Marx; Patterson; Roszkowski; Schuler; Unger; Wagner; Wallach
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 616 - 627
