2-甲基-1-噻吩-2-丙烷-1-酮合成路线 （共 18 条）
参考文献
Modder, Johan F.; Leijen, Ronald J.; Vrieze, Kees; Smeets, Wilberth J. J.; Spek, Anthony L.; Koten, Gerard van
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1995 , # 24 p. 4021 - 4028
参考文献
Gubler, Marcel; Haap, Wolfgang; Hebeisen, Paul; Kitas, Eric A.; Kuhn, Bernd; Minder, Rudolf E.; Schott, Brigitte; Wessel, Hans P.
Patent: US2007/281979 A1, 2007 ;
Location in patent: Page/Page column 15 ;
反应条件
pyridinium chlorochromate
参考文献
Pfoertner, Karl-Heinz
Helvetica Chimica Acta, 1980 , vol. 63, # 3 p. 645 - 652
反应条件
boron trifluoride diethyl etherate
参考文献
Liska, Robert
Heterocycles, 2001 , vol. 55, # 8 p. 1475 - 1486
反应条件
1: isopropylmagnesium chloride With indium(III) chloride in tetrahydrofuran; hexane T=-78 - 20°C; 2: thien-2-yl bromide; carbon monoxide With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane T=60°C; 2 h;
参考文献
Lee, Sung Wook; Lee, Kooyeon; Seomoon, Dong; Kim, Sundae; Kim, Hyunseok; Kim, Hyun; Shim, Eunkyong; Lee, Miae; Lee, Seokju; Kim, Misook; Lee, Phil Ho
Journal of Organic Chemistry, 2004 , vol. 69, # 14 p. 4852 - 4855
反应条件
potassium hydroxide; 18-crown-6 ether in benzene T=25°C; 12.5 h; var. time, other alkyl and benzyl halides, other heterocyclic ketones; Product distribution;
参考文献
Abele, E. M.; Gol'dberg, Yu. Sh.; Popelis, Yu. Yu.; Shimanskaya, M. V.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 8 p. 1545 - 1550
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 8 p. 1784 - 1790
反应条件
1: 1-(thien-2-yl)-1-propanone With lithium hexamethyldisilazane T=-78°C; 2: methyl iodide
参考文献
Liang, Yu-Feng; Jiao, Ning
Angewandte Chemie - International Edition, 2014 , vol. 53, # 2 p. 548 - 552
Angew. Chem., 2014 , vol. 53, # 2 p. 558 - 562,5
反应条件
1: 93.3 percent / Grignard-reaction 2: 91 percent / pyridinium chlorochromate View Scheme
参考文献
Pfoertner, Karl-Heinz
Helvetica Chimica Acta, 1980 , vol. 63, # 3 p. 645 - 652
反应条件
tetrachlorosilane; benzene Erwaermen der Reaktionsloesung mit Thiophen und Zinn(IV)-chlorid;
参考文献
Jur'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 3873,3878; engl. Ausg. S. 3831, 3836
反应条件
1,1,2,2-tetramethylethylene; oxygen Irradiation;
参考文献
Oda, Kazuaki; Machida, Minoru; Kanaoka, Yuichi
Heterocycles, 1984 , vol. 21, # 2 p. 622
