2-氟-4-硝基苯甲酸乙酯合成路线 （共 7 条）
反应条件
sulfuric acid Heating / reflux;
参考文献
Ackermann, Jean; Bleicher, Konrad; Ceccarelli Grenz, Simona M.; Chomienne, Odile; Mattei, Patrizio; Schulz-Gasch, Tanja
Patent: US2007/60567 A1, 2007 ;
Location in patent: Page/Page column 20-21 ;
反应条件
1: SOCl2 / 80 °C 2: pyridine / CH2Cl2 View Scheme
参考文献
Bristol-Myers Squibb Co.
Patent: US5648385 A1, 1997 ;
反应条件
pyridine in thionyl chloride; ethanol; dichloromethane
参考文献
Allergan
Patent: US5675024 A1, 1997 ;
反应条件
nitrogen; sodium hydrogencarbonate in dichloromethane; isobutyramide
参考文献
THE WELLCOME FOUNDATION LIMITED
Patent: EP728018 B1, 2003 ;
反应条件
1: Na2Cr2O7, H2SO4 / acetic acid / 90 °C 2: SOCl2 / 80 °C 3: pyridine / CH2Cl2 View Scheme
参考文献
Teng; Duong; Klein; Pino; Chandraratna
Journal of Medicinal Chemistry, 1996 , vol. 39, # 16 p. 3035 - 3038
反应条件
pyridine in dichloromethane Yield given;
参考文献
Teng; Duong; Klein; Pino; Chandraratna
Journal of Medicinal Chemistry, 1996 , vol. 39, # 16 p. 3035 - 3038
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Teng; Duong; Klein; Pino; Chandraratna
Journal of Medicinal Chemistry, 1996 , vol. 39, # 16 p. 3035 - 3038
