(R)-(+)-N-乙酰基-甲基苄胺合成路线 （共 87 条）
反应条件
chiral [2,2']-diphospholanyl-based Rh(I); hydrogen in methanol T=20°C; P=1034.3 Torr; 12 h;
参考文献
Gridnev; Yasutake; Higashi; Imamoto
Journal of the American Chemical Society, 2001 , vol. 123, # 22 p. 5268 - 5276
反应条件
Candida antarctica lipase B; bis[(p-MeOC6H4)-4-cyclopentadienol]Ru2(CO)4; sodium carbonate in toluene T=90°C; 72 h;
参考文献
Thalen, Lisa K.; Zhao, Dongbo; Sortais, Jean-Baptiste; Paetzold, Jens; Hoben, Christine; Baeckvall, Jan-E.
Chemistry - A European Journal, 2009 , vol. 15, # 14 p. 3403 - 3410
反应条件
triethylamine in diethyl ether 19 h; Heating;
参考文献
Duhamel, Lucette; Plaquevent, Jean-Christophe
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 1-2 p. 75 - 83
反应条件
hydrogen; palladium on aluminium oxyhydroxide T=100°C; 4 h; Product distribution / selectivity;
参考文献
Postech Academy-Industry Foundation
Patent: US7592488 B2, 2009 ;
Location in patent: Page/Page column 18 ;
反应条件
lt;lt;(R,R)-1,2-bis(trans-2,5-dimethylphospholano)ethanegt;Rh(COD)gt;OTf; hydrogen in methanol T=22°C; P=3102.9 Torr; 15 h; var. rhodium chiral complexes and solvents; other aryl enamides; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 118, # 21 p. 5142 - 5143
反应条件
Candida antarctica lipase B; hydrogen; N-ethyl-N,N-diisopropylamine; 5percent Pd/C in toluene T=60°C; 120 h;
参考文献
Choi; Kim; Ahn
Organic letters, 2001 , vol. 3, # 25 p. 4099 - 4101
反应条件
hydrogen in tetrahydrofuran
参考文献
The Hong Kong Polytechnic University
Patent: US5919981 A1, 1999 ;
反应条件
oxygen; rose bengal in acetonitrile T=13°C; 5 h; Irradiation;
参考文献
Journal of Organic Chemistry, , vol. 57, # 1 p. 229 - 234
反应条件
1: Ti(OEt)4 / CH2Cl2 / Heating 2: m-CPBA / CH2Cl2 / 20 °C 3: H2 / Pd(OCOCF3)2; (S,S,R,R)-TangPhos / CH2Cl2 / 24 h / 40 °C / 57000 Torr 4: naphthalene; Na / 1,2-dimethoxy-ethane / 1 h / 20 °C 5: CH2Cl2 View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 23 p. 3832 - 3835
反应条件
in chloroform T=0°C;
参考文献
Paleek, Jii; Zweigerdt, Robert; Olmer, Ruth; Martin, Ulrich; Kirschning, Andreas; Draeger, Gerald
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5503 - 5510
