N-乙酰-L-苯丙氨酸甲酯合成路线 （共 84 条）
反应条件
4-methyl-morpholine; 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride
参考文献
TOKUYAMA CORPORATION
Patent: EP1178043 A1, 2002 ;
Location in patent: Page 31, 32 ;
反应条件
subtilisin Carlsberg type VIII in carbon dioxide; water T=47°C; P=85329.4 Torr;
参考文献
Australian Journal of Chemistry, , vol. 55, # 4 p. 259 - 262
反应条件
in toluene T=110°C; 24 h;
参考文献
Gibson, Sarah; Romero, Dickie; Jacobs, Hollie K.; Gopalan, Aravamudan S.
Tetrahedron Letters, 2010 , vol. 51, # 51 p. 6737 - 6740
参考文献
Journal of the American Chemical Society, , vol. 74, p. 101,105
反应条件
bis(.eta.(2)-ethylene)(2,4,-pentanedionato)rhodium; NAF in 1,4-dioxane; water T=100°C; 5 h; Title compound not separated from byproducts.;
参考文献
Organic Letters, , vol. 3, # 25 p. 4083 - 4085
反应条件
bis(norbornadiene)rhodium(I) tetrafluoroborate; (S(p),S(p))-2,2''-bis[bis(3,5-dimethylphenyl)phosphino]-1,1''-biferrocene; hydrogen in methanol T=25°C; P=3750.38 Torr; 15 h; Autoclave; optical yield given as percent ee;
参考文献
Dalton Transactions, , # 15 p. 2751 - 2763
反应条件
in acetonitrile T=80°C; 1 h; Inert atmosphere;
参考文献
Taylor, James E.; Jones, Matthew D.; Williams, Jonathan M. J.; Bull, Steven D.
Journal of Organic Chemistry, 2012 , vol. 77, # 6 p. 2808 - 2818
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C55H31BF22N2O2P(1-)*C16H36N(1+); hydrogen in dichloromethane T=20°C; P=7500.75 Torr; 1 h; Inert atmosphereSchlenk technique; Reagent/catalystSolvent; enantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 19, # 7 p. 2405 - 2415
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; hydrogen in toluene T=20°C; P=7500.75 Torr; 1 h; Inert atmosphereSchlenk technique; Reagent/catalystSolvent; enantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 19, # 7 p. 2405 - 2415
反应条件
Rhizobium meliloti cyclosophoraoses T=60°C; 11 h; KineticsEnzyme kinetics; Further Variations:Reaction partnersreaction time;
参考文献
Park, Heylin; Jung, Seunho
Carbohydrate Research, 2008 , vol. 343, # 2 p. 274 - 281
