3-羟基-3,3-二(苯基)丙酸合成路线 （共 21 条）
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2006/117754 A1, 2006 ;
Location in patent: Page/Page column 21-22 ;
WO 2006/117754 A1
参考文献
Adam,W. et al.
Journal of the American Chemical Society, 1972 , vol. 94, p. 2000 - 2006
反应条件
1: With iodine; mercury dichloride; zinc in tetrahydrofuran T=0°C; Reformatsky reaction; Inert atmosphere; 2: With hydrogenchloride; water in benzene T=0°C; Reformatsky reaction;
参考文献
Savic, Jelena S.; Dilber, Sanda P.; Markovic, Bojan D.; Milenkovic, Marina T.; Vladimirov, Sote M.; Juranic, Ivan O.
Molecules, 2011 , vol. 16, # 8 p. 6645 - 6655
反应条件
potassium hydroxide in methanol T=40°C; 4 h; Inert atmosphere;
参考文献
Grajewska, Agnieszka; Oestreich, Martin
Synlett, 2010 , # 16 p. 2482 - 2484
参考文献
Nieuwland; Daly
Journal of the American Chemical Society, 1931 , vol. 53, p. 1842,1843
参考文献
Oku, Akira; Yokoyama, Taka-aki; Harada, Toshiro
Tetrahedron Letters, 1983 , vol. 24, # 43 p. 4699 - 4702
反应条件
N,N,N',N'-tetramethylbenzidine in acetonitrile T=2°C; UV-irradiation; Product distributionQuantum yield; Further Variations:ReagentsTemperatures;
参考文献
Ito, Yoshikatsu
Tetrahedron, 2007 , vol. 63, # 15 p. 3108 - 3114
反应条件
potassium permanganate
参考文献
Tarassow
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1909 , vol. 41, p. 1309
Chem. Zentralbl., 1910 , vol. 81, # I p. 739
反应条件
1: zinc; benzene / Zersetzen des Reaktionsproduktes mit verd. Schwefelsaeure 2: methanolic KOH-solution View Scheme
参考文献
Rupe; Busolt
Chemische Berichte, 1907 , vol. 40, p. 4538
反应条件
n-butyllithium; naphthalenyllithium Multistep reaction;
参考文献
Barluenga, Jose; Florez, Josefa; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 3019 - 3026
