2-乙酰氨基-2-苯基乙酸甲酯合成路线 （共 5 条）
反应条件
lithium hydroxide hydrate in methanol T=20°C; 2 h;
参考文献
Bressi, Jerome C.; Jong, Ron de; Wu, Yiqin; Jennings, Andy J.; Brown, Jason W.; O'Connell, Shawn; Tari, Leslie W.; Skene, Robert J.; Vu, Phong; Navre, Marc; Cao, Xiaodong; Gangloff, Anthony R.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 10 p. 3138 - 3141
反应条件
1: 87 percent / NBS, α,α'-azobis(isobutyronitrile) / CCl4 / 3 h / Ambient temperature 2: 83 percent / aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature 3: 2.6 g / ethyl acetate / 0.33 h / Heating View Scheme
参考文献
Koeppen, Juergen; Matthies, Dieter; Schweim, Harald
Liebigs Annalen der Chemie, 1985 , # 12 p. 2383 - 2389
反应条件
With lithium hydroxide hydrate in methanol T=20°C; 2 h;
参考文献
Bressi, Jerome C.; Jong, Ron de; Wu, Yiqin; Jennings, Andy J.; Brown, Jason W.; O'Connell, Shawn; Tari, Leslie W.; Skene, Robert J.; Vu, Phong; Navre, Marc; Cao, Xiaodong; Gangloff, Anthony R. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 10 p. 3138 - 3141
反应条件
With N-bromosuccinmide; azobisisobutyronitrile in tetrachloromethane 3 h; Ambient temperature;
参考文献
Koeppen, Juergen; Matthies, Dieter; Schweim, Harald Liebigs Annalen der Chemie, 1985 , # 12 p. 2383 - 2389
反应条件
Multi-step reaction with 2 steps 1: 87 percent / NBS, α,α'-azobis(isobutyronitrile) / CCl4 / 3 h / Ambient temperature2: 83 percent / aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature
参考文献
Koeppen, Juergen; Matthies, Dieter; Schweim, Harald Liebigs Annalen der Chemie, 1985 , # 12 p. 2383 - 2389
