2,3,4,5-四甲氧基甲苯合成路线 （共 45 条）
反应条件
copper(I) bromide in tetrahydrofuran
参考文献
Kuraray Co., Ltd.
Patent: US4270003 A1, 1981 ;
反应条件
CH3I; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran; hexane
参考文献
Frost, John W.; Hansen, Chad A.
Patent: US2004/209337 A1, 2004 ;
反应条件
1: SnCl2; aq. HCl / ethanol 2: 990 mg / aq. KOH / 1 h / 80 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 16 p. 2371 - 2375
反应条件
sodium hydroxide in ethanol; water 0.75 h; Ambient temperature;
参考文献
Lipshutz, Bruce H.; Kim, Sung-Kyu; Mollard, Paul; Stevens, Kirk L.
Tetrahedron, 1998 , vol. 54, # 7 p. 1241 - 1253
反应条件
1: 1.) Cl2C(O), pyridine, 2.) H2SO4, HNO3, 3.) aq. KOH 2: Zn, HCl 3: H2O / Heating 4: 69 percent / NaOH 5: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
反应条件
1: 11 percent / K3Fe(CN)6, H2O2, AcOH 2: 100 percent / H2 / 10 percent Pd/C / ethanol 3: 69 percent / NaOH 4: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
反应条件
1: 2,3-Dimethoxy-5-methyl-1,4-benzoquinone With palladium on activated charcoal; hydrogen in methanol T=20°C; 2: dimethyl sulfate With potassium carbonate in acetone RefluxInert atmosphere;
参考文献
Yamakoshi, Hiroyuki; Dodo, Kosuke; Palonpon, Almar; Ando, Jun; Fujita, Katsumasa; Kawata, Satoshi; Sodeoka, Mikiko
Journal of the American Chemical Society, 2012 , vol. 134, # 51 p. 20681 - 20689
反应条件
1: 95 percent / HCO2H, H2O2 / CH2Cl2 / 0 - 20 °C 2: 80 percent / H2 / 10 percent Pd/C / ethanol 3: 69 percent / NaOH 4: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
反应条件
1: 80 percent / H2 / 10 percent Pd/C / ethanol 2: 69 percent / NaOH 3: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
反应条件
1: 100 percent / H2 / 10 percent Pd/C / ethanol 2: 69 percent / NaOH 3: 1.) n-BuLi, TMEDA / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 15 p. 3799 - 3800
