反式,反式-1,3-丁二烯-1,4-二羧酸合成路线 （共 65 条）
反应条件
hydrogen; Ru10Pt2 in ethanol T=79.85°C; P=22501.8 Torr; 5 h; Product distribution; Further Variations:Catalysts;
参考文献
Thomas, John Meurig; Raja, Robert; Johnson, Brian F. G.; O'Connell, Timothy J.; Sankar, Gopinathan; Khimyak, Tetyana
Chemical Communications, 2003 , # 10 p. 1126 - 1127
反应条件
1: sulfuric acid / 18 h / Reflux 2: ammonia / ethanol; water / 336 h / 20 °C 3: hydrogen / Cr2Cu2O5 / tetrahydrofuran / 5 h / 300 °C / 27409.6 Torr View Scheme
参考文献
Strategic Enzyme Applications, Inc.
Patent: US2012/107886 A1, 2012 ;
Location in patent: Page/Page column Sheet 4 ;
反应条件
1: Na-Hg / aq. NaOH / 0 °C 2: H2SO4 / toluene / Heating 3: (i) NaOEt, EtOH, (ii) /BRN= 1783790/ 4: (i) aq. HCl, (ii) /BRN= 1098229/, H2SO4 5: (i) pyrrolidine, TsOH, benzene, (ii) /BRN= 1697767/, dioxane 6: H2 / Pd-BaSO4, quinoline / petroleum ether View Scheme
参考文献
Demole,E.; Stoll,M.
Helvetica Chimica Acta, 1962 , vol. 45, p. 692 - 703
反应条件
1: Na-Hg / aq. NaOH / 0 °C 2: H2SO4 / toluene / Heating View Scheme
参考文献
Demole,E.; Stoll,M.
Helvetica Chimica Acta, 1962 , vol. 45, p. 692 - 703
反应条件
1: sulfuric acid / 18 h / Reflux 2: ammonia / ethanol; water / 336 h / 20 °C 3: hydrogen; ammonia / Cr2Cu2O5 / tetrahydrofuran / 5 h / 250 °C / 85331.7 Torr View Scheme
参考文献
AMYRIS, INC.; BUI, Vu; FROST, John W.
Patent: WO2012/141993 A1, 2012 ;
反应条件
hydrogen T=210°C; 5 h;
参考文献
She, Xiaoyan; Brown, Heather M.; Zhang, Xiao; Ahring, Birgitte K.; Wang, Yong
ChemSusChem, 2011 , vol. 4, # 8 p. 1071 - 1073
反应条件
1: sulfuric acid / 18 h / Reflux 2: ammonia / ethanol; water / 336 h / 20 °C 3: hydrogen / Cr2Cu2O5 / tetrahydrofuran / 5 h / 300 °C / 27409.6 Torr View Scheme
参考文献
AMYRIS, INC.; BUI, Vu; FROST, John W.
Patent: WO2012/141993 A1, 2012 ;
参考文献
WO2012/75053 A2, ;
Page/Page column 83 ;
反应条件
1: sulfuric acid / 18 h / Reflux 2: ammonia / ethanol; water / 336 h / 20 °C 3: hydrogen / Cr2Cu2O5 / tetrahydrofuran / 5 h / 300 °C / 27409.6 Torr 4: trichlorophosphate / Reflux View Scheme
反应条件
1: sulfuric acid / 16 h / Reflux 2: hydroquinone / m-xylene / 72 h / Inert atmosphere; Reflux 3: oxygen / platinum on carbon / m-xylene / 96 h / Reflux View Scheme
参考文献
AMYRIS, INC.; SCHWEITZER, Dirk, Ph.D.
Patent: WO2012/82725 A1, 2012 ;
