S-甲基异硫氨基脲盐酸盐合成路线 （共 35 条）
反应条件
in ethanol T=60°C; 0.5 h;
参考文献
Allergan, Inc.
Patent: US2008/64872 A1, 2008 ;
Location in patent: Page/Page column 28 ;
US 20080064872 A1
反应条件
sodium acetate in ethanol; water 4 h; Heating;
参考文献
Molina, Pedro; Arques, Antonio; Cartagena, Inmaculada; Alias, Maria Asuncion; Concepcion Foces-Foces, Maria de la; Cano, Felix Hernandez
Liebigs Annalen der Chemie, 1988 , p. 133 - 140
反应条件
potassium hydrogencarbonate in ethanol 3 h; Heating;
参考文献
Emilsson, Hakan
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1077 - 1081
反应条件
beim Behandeln mit NaOH im Luftstrom;
参考文献
Scott; Reilly
Chemistry and Industry (London, United Kingdom), 1952 , p. 907
反应条件
sodium hydrogen selenide in ethanol
参考文献
Klayman,D.L.; Shine,R.J.
Journal of Organic Chemistry, 1969 , vol. 34, p. 3549 - 3551
反应条件
sodium hydrogencarbonate in ethanol; water T=0 - 20°C; Title compound not separated from byproducts.;
参考文献
Carroll, F. Ivy; Kotturi, Sharadsrikar V.; Navarro, Hernan A.; Mascarella, S. Wayne; Gilmour, Brian P.; Smith, Forrest L.; Gabra, Bichoy H.; Dewey, William L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3388 - 3391
参考文献
Heilman; Scozzie; Wayner; Gullo; Ariyan
Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 3 p. 282 - 287
反应条件
sodium hydrogencarbonate in ethanol; water 2 h; Reflux; regioselective reaction;
参考文献
Lv, Wei; Banerjee, Biplab; Molland, Katrina L.; Seleem, Mohamed N.; Ghafoor, Adil; Hamed, Maha I.; Wan, Baojie; Franzblau, Scott G.; Mesecar, Andrew D.; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 406 - 418
反应条件
sodium hydrogencarbonate in water 0.166667 h; Cooling with ice;
参考文献
Ban, Kung; Duffy, Sandra; Khakham, Yelena; Avery, Vicky M.; Hughes, Andrew; Montagnat, Oliver; Katneni, Kasiram; Ryan, Eileen; Baell, Jonathan B.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 20 p. 6024 - 6029
反应条件
1.) H2O, room temp., 30 min., 2.) glacial AcOH, reflux, 1 h;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 329, # 2 p. 290 - 300
