3-氯-1,1-二乙氧基丙烷合成路线 （共 57 条）
反应条件
tetra-(n-butyl)ammonium iodide in dimethyl sulfoxide T=50°C; 15 h;
参考文献
Wang, Lihong; Prabhudas, Bodhuri; Clive, Derrick L. J.
Journal of the American Chemical Society, 2009 , vol. 131, p. 6003 - 6012
反应条件
ethanol; glycerol T=115 - 120°C; unter Druck;
参考文献
Wohl
Chemische Berichte, 1906 , vol. 39, p. 1953
反应条件
methanol; potassium iodide T=120°C;
参考文献
Anderson,E.; Capon,B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1972 , p. 515 - 522
反应条件
sodium hydroxide; water T=115°C;
参考文献
Wohl; Emmerich
Chemische Berichte, 1900 , vol. 33, p. 2763
参考文献
Brabant
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1913 , vol. 86, p. 212
反应条件
1: 3-chloro-propionaldehyde diethyl acetal With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran
T=-78°C; 1 h;
2: With zinc dibromide in tetrahydrofuran
T=-78 - 20°C;
3: para-bromoacetophenone With Pd(OAc)2(PPh3)2 in tetrahydrofuran
T=70°C; Negishi cross-coupling reaction; Further stages.;
参考文献
Yus, Miguel; Gomis, Joaquin
European Journal of Organic Chemistry, 2002 , # 12 p. 1989 - 1995
反应条件
1-methyl-pyrrolidin-2-one; palladium diacetate; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=20°C; Kumada coupling; 20 h;
参考文献
Frisch, Anja C.; Shaikh, Nadim; Zapf, Alexander; Belier, Matthias
Angewandte Chemie - International Edition, 2002 , vol. 41, # 21 p. 4056 - 4059
反应条件
diethyl ether; phenyllithium
参考文献
Jones; Law
Journal of the Chemical Society, 1958 , p. 3631
反应条件
boron trifluoride diethyl etherate; water; naphthalenyllithium; 3-chloro-benzenecarboperoxoic acid
1.) THF, -78 deg C, 6 h, 2.) 20 deg C, 2 h, 3.) CH2Cl2; Yield given. Multistep reaction;
参考文献
Barluenga, Jose; Fernandez, Jose R.; Yus, Miguel
Journal of the Chemical Society, Chemical Communications, 1987 , # 20 p. 1534 - 1535
参考文献
Wang, Lihong; Prabhudas, Bodhuri; Clive, Derrick L. J.
Journal of the American Chemical Society, 2009 , vol. 131, p. 6003 - 6012
