1-(2-甲基苯基)-1H-吡咯-2-甲醛合成路线 （共 8 条）
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; Reflux; 2: 1-(2-methylphenyl)pyrrole in anhydrous dichloroethane Vilsmeier-Haack reaction; 2 h; Reflux; 3: With water; sodium acetate
参考文献
Paillet-Loilier, Magalie; Fabis, Frederic; Lepailleur, Alban; Bureau, Ronan; Butt-Gueulle, Sabrina; Dauphin, Francois; Delarue, Catherine; Vaudry, Hubert; Rault, Sylvain
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3753 - 3757
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h; regioselective reaction;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h; regioselective reaction;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: 80 percent / acetic acid / 2 h / Heating 2: POCl3 / 1 h / 0 - 80 °C View Scheme
参考文献
Paillet-Loilier, Magalie; Fabis, Frederic; Lepailleur, Alban; Bureau, Ronan; Butt-Gueulle, Sabrina; Dauphin, Francois; Delarue, Catherine; Vaudry, Hubert; Rault, Sylvain
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3753 - 3757
