2-碘-1,1,1-三氟乙烷合成路线 （共 59 条）
反应条件
potassium fluoride in dimethyl sulfoxide
T=120 - 130°C; 3 h;
参考文献
Kamal, Ahmed; Pratap; Ramana, K.Venkata; Ramana; Babu, A.Hari
Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7353 - 7355
反应条件
sodium azide; methyl-tridecylammonium chloride
T=90 - 100°C;
参考文献
Palomo, Claudio; Aizpurua, Jesus M.; Loinaz, Iraida; Fernandez-Berridi, Maria Jose; Irusta, Lourdes
Organic Letters, 2001 , vol. 3, # 15 p. 2361 - 2364
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=60°C; 18 h;
参考文献
EXELIXIS, INC.; WILLIAMS, Matthew, A.
Patent: WO2012/61337 A1, 2012 ;
Location in patent: Page/Page column 48; 49 ;
WO 2012/061337 A1
参考文献
Ferguson Bert E Holmes, John D.
International Journal of Chemical Kinetics, 2001 , vol. 33, # 10 p. 549 - 557
反应条件
potassium fluoride in dimethyl sulfoxide
T=120 - 130°C; 4 h;
参考文献
Kamal, Ahmed; Pratap; Ramana, K.Venkata; Ramana; Babu, A.Hari
Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7353 - 7355
反应条件
copper in dimethyl sulfoxide
T=120°C; 55 h; Schlenk techniqueInert atmosphereSealed tube;
参考文献
Xu, Song; Chen, Huan-Huan; Dai, Jian-Jun; Xu, Hua-Jian
Organic Letters, 2014 , vol. 16, # 9 p. 2306 - 2309
反应条件
tris-(dibenzylideneacetone)dipalladium(0); water; cesium fluoride; copper(l) chloride; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in N,N-dimethyl-formamide
T=65°C; 16 h; Inert atmosphere;
参考文献
Liang, Apeng; Li, Xinjian; Liu, Dongfeng; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Chemical Communications, 2012 , vol. 48, # 66 p. 8273 - 8275
反应条件
sodium hydride in various solvent(s)
T=120°C; 18 h;
参考文献
Hammond, Gerald B.; Plevey, Raymond G.; Sampson, Paul; Tatlow, John Colin
Journal of Fluorine Chemistry, 1988 , vol. 40, p. 81 - 98
反应条件
bis(η3-allyl-μ-chloropalladium(II)); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide
T=80°C; 1 h;
参考文献
Hwang, Jinil; Park, Kyungho; Choe, Juseok; Min, Hongkeun; Song, Kwang Ho; Lee, Sunwoo
Journal of Organic Chemistry, 2014 , vol. 79, # 7 p. 3267 - 3271
