(Z)-2-(吡咯烷-2-亚基)乙酸乙酯合成路线 （共 8 条）
反应条件
pyridine in dichloromethane T=-10 - -5°C;
参考文献
Cheng, Ying; Yang, Hai-Bo; Wang, Mei-Xiang; Williams, David J
Tetrahedron, 2002 , vol. 58, # 14 p. 2821 - 2829
反应条件
in benzene
1 h; Heating;
参考文献
Nagasaka, Tatsuo; Inoue, Hitoshi; Hamaguchi, Fumiko
Heterocycles, 1983 , vol. 20, # 6 p. 1099 - 1107
参考文献
Zhang, Yong Jian; Park, Jung Hwan; Lee, Sang-Gi
Tetrahedron Asymmetry, 2004 , vol. 15, # 14 p. 2209 - 2212
反应条件
in toluene
Addition; Michael addition; condensation; 144 h; Heating;
参考文献
Wang, Mei-Xiang; Miao, Wei-Shi; Cheng, Ying; Huang, Zhi-Tang
Tetrahedron, 1999 , vol. 55, # 51 p. 14611 - 14622
反应条件
1: 74 percent / ethanol / 16 h / Heating
2: 63 percent / sodium ethoxide / ethanol / 2 h / Heating
View Scheme
参考文献
Nagasaka, Tatsuo; Inoue, Hitoshi; Hamaguchi, Fumiko
Heterocycles, 1983 , vol. 20, # 6 p. 1099 - 1107
反应条件
in benzene
158 h; Heating;
参考文献
Nagasaka, Tatsuo; Inoue, Hitoshi; Hamaguchi, Fumiko
Heterocycles, 1983 , vol. 20, # 6 p. 1099 - 1107
反应条件
1: 97 percent / benzene / Heating
2: 1.) cupric acetate, pyridine, 2.) lead tetraacetate / 1.) benzene, RT, 2.) a.) benzene, RT, 2 h, b.) reflux, 1 h
3: 100 percent / methanol / 3 h / Heating
View Scheme
参考文献
Nagasaka, Tatsuo; Inoue, Hitoshi; Hamaguchi, Fumiko
Heterocycles, 1983 , vol. 20, # 6 p. 1099 - 1107
反应条件
1: α-(tetrahydropyrrolidinylidene-2) acetate d'ethyle With sodium hydride in N,N-dimethyl-formamide
T=-30°C; 0.166667 h; Inert atmosphere;
2: 1,3-dibromo-propane in N,N-dimethyl-formamide
T=-30°C; 0.5 h; Inert atmosphere;
参考文献
Kim, Ju Hyun; Shin, Hyunik; Lee, Sang-Gi
Journal of Organic Chemistry, 2012 , vol. 77, # 3 p. 1560 - 1565
