5-二甲基氨基萘-1-(n-(2-氨基乙基))磺酰胺合成路线 （共 15 条）
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Kurono, Masakuni; Isobe, Minoru
Chemistry Letters, 2004 , vol. 33, # 4 p. 452 - 453
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 18 h;
参考文献
Knighton, Richard C.; Sambrook, Mark R.; Vincent, Jack C.; Smith, Simon A.; Serpell, Christopher J.; Cookson, James; Vickers, Matthew S.; Beer, Paul D.
Chemical Communications, 2013 , vol. 49, # 23 p. 2293 - 2295
反应条件
morpholine in N,N-dimethyl-formamide T=20°C; 0.5 h;
参考文献
Larroque-Lombard, Anne-Laure; Todorova, Margarita; Golabi, Nahid; Williams, Christopher; Jean-Claude, Bertrand J.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2104 - 2113
反应条件
hydrazine hydrate in methanol 2 h; Heating;
参考文献
Kondo, Hiroki; Takaki, Katsunori; Kuroki, Ryoichi; Tada, Akihiro; Fukumoto, Kunihiro; Sunamoto, Junzo
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 10 p. 2957 - 2961
反应条件
1: With triphenylphosphine in dichloromethane T=20°C; 2 h; 2: With water in dichloromethane T=20°C; 16 h;
参考文献
Kele, Peter; Li, Xiaohua; Link, Martin; Nagy, Krisztina; Herner, Andras; Lrincz, Krisztian; Beni, Szabolcs; Wolfbeis, Otto S.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 17 p. 3486 - 3490
反应条件
triethylamine in dichloromethane T=20°C; 3 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3486 - 3490
反应条件
1: trypsin 2: HOBT; HBTU; DIEA / 1-methyl-pyrrolidin-2-one 3: TFA; m-cresol; thioanisole 4: V8 protease View Scheme
参考文献
Chemistry - A European Journal, , vol. 11, # 24 p. 7294 - 7304
反应条件
1: V8 protease 2: HOBT; HBTU; DIEA / 1-methyl-pyrrolidin-2-one 3: TFA; m-cresol; thioanisole 4: trypsin View Scheme
参考文献
Chemistry - A European Journal, , vol. 11, # 24 p. 7294 - 7304
反应条件
1: Et3N / CHCl3 / 0.58 h 2: trifluoroacetic acid / 1 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 20 p. 2975 - 2982
反应条件
1: 95 percent / SOCl2 / CHCl3 / 4 h / Heating 2: 76 percent / dimethylformamide / 3 h / 100 °C 3: 72 percent / N2H4*H2O / methanol / 2 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 57, # 10 p. 2957 - 2961
