3-(2-甲基苯基)恶二唑-3-鎓-5-醇合成路线 （共 4 条）
反应条件
TBBDA; acetic anhydride; sodium nitrite in dichloromethane T=0 - 5°C; 7 h;
参考文献
Azarifar, Davood; Ghasemnejad-Bosra, Hassan; Ghorbani-Vaghei, Ramin; Tajbaksh, Mahmood
Heterocycles, 2006 , vol. 68, # 11 p. 2343 - 2347
反应条件
1,3-dibromo-5,5-dimethyl-hydantoin in dichloromethane T=0 - 5°C; 4 h;
参考文献
Azarifar, Davood; Bosra, Hassan Ghasemnejad; Zolfigol, Mohammad-Ali; Tajbaksh, Mahmood
Heterocycles, 2006 , vol. 68, # 1 p. 175 - 181
反应条件
1.1: SiO2 / 0.13 h / 20 °C / microwave irradiation 1.2: 85 percent / aq. sodium hydroxide / ethanol / 0.17 h / Heating 2.1: 92 percent / silica chloride; wet SiO2; sodium nitrite / CH2Cl2 / 2 h / 0 - 5 °C 3.1: 80 percent / 1,3-dibromo-5,5-dimethylhydantoin / CH2Cl2 / 4 h / 0 - 5 °C View Scheme
参考文献
Azarifar, Davood; Bosra, Hassan Ghasemnejad; Zolfigol, Mohammad-Ali; Tajbaksh, Mahmood
Heterocycles, 2006 , vol. 68, # 1 p. 175 - 181
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1.) THF, 0.5 h, -78 deg C, 2.) THF, -78 deg C, 1 h; Multistep reaction;
参考文献
Turnbull, Kenneth; Sun, Congcong; Krein, Douglas M.
Tetrahedron Letters, 1998 , vol. 39, # 12 p. 1509 - 1512
