4,4'-二氟二苯甲酮合成路线 （共 115 条）
反应条件
tert.-butylhydroperoxide; vanadium pentoxide in water T=100°C; 6 h;
参考文献
Alagiri, Kaliyamoorthy; Prabhu, Kandikere Ramaiah
Tetrahedron, 2011 , vol. 67, # 44 p. 8544 - 8551
反应条件
C28H40Br4N4Pd2; potassium carbonate in ethanol; water T=50°C; Suzuki Coupling; 2 h;
参考文献
Gupta, Sumanta; Basu, Basudeb; Das, Sajal
Tetrahedron, 2013 , vol. 69, # 1 p. 122 - 128
反应条件
potassium carbonate; chlorobenzene; 2-dicyclohexylphosphino-1,1'-biphenyl; bis(dibenzylideneacetone)-palladium(0) in toluene T=105°C; 12 h;
参考文献
Symyx Technologies, Inc.
Patent: US6350916 B1, 2002 ;
Location in patent: Example 1 ;
反应条件
pyridine; tert.-butylhydroperoxide; air; K(1+)*AuCl4(1-)*0.5H2O=K[AuCl4]*0.5H2O in decane T=90°C; 24 h;
参考文献
Li, Huanrong; Li, Zhiping; Shi, Zhangjie
Tetrahedron, 2009 , vol. 65, # 9 p. 1856 - 1858
反应条件
1-methyl-pyrrolidin-2-one; cesium fluoride in water; benzene
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US4453009 A1, 1984 ;
反应条件
potassium fluoride in water; isopropyl alcohol; benzene
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US4453009 A1, 1984 ;
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I); di-tert-butyl peroxide; 1,2-bis-(diphenylphosphino)ethane in benzene T=160°C; 12 h; Inert atmosphere; chemoselective reaction;
参考文献
Yang, Luo; Zeng, Tieqiang; Shuai, Qi; Guo, Xiangyu; Li, Chao-Jun
Chemical Communications, 2011 , vol. 47, # 7 p. 2161 - 2163
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US4453009 A1, 1984 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane T=80°C; 4 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Venkatesh, Varadhachari; Dasgupta, Priyabrata
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 4975 - 4980
反应条件
1: 1-bromo-4-fluorobenzene With n-butyllithium in diethyl ether; hexane T=-50 - -30°C; Metallation; 3 h; 2: N,N-dimethylcarbamoyl chloride in diethyl ether; hexane T=-50 - 0°C; Acylation; 3 h;
参考文献
Lucas; El Mehdi; Ho; Belanger; Breau
Synthesis, 2000 , # 9 p. 1253 - 1258
