N-(3-苯基丙基)乙酰胺合成路线 （共 13 条）
反应条件
XtalFluor-M® T=20°C; Ritter reaction; 1.5 h;
参考文献
OMEGACHEM INC.; COUTURIER, Michel; L'HEUREUX, Alexandre
Patent: WO2010/145037 A1, 2010 ;
Location in patent: Page/Page column 37 ;
反应条件
triethylamine T=20°C;
参考文献
Ha-Duong; Dijols; Marques-Soares; Minoletti; Dansette; Mansuy
Journal of Medicinal Chemistry, 2001 , vol. 44, # 22 p. 3622 - 3631
反应条件
L-proline in neat (no solvent) T=100°C; 36 h; Sealed tube;
参考文献
Rao, Sadu Nageswara; Mohan, Darapaneni Chandra; Adimurthy, Subbarayappa
Organic Letters, 2013 , vol. 15, # 7 p. 1496 - 1499
反应条件
in dichloromethane T=20°C; 16 h;
参考文献
Roice, Michael; Christensen, Soren F.; Meldal, Morten
Chemistry - A European Journal, 2004 , vol. 10, # 18 p. 4407 - 4415
反应条件
1: 1-amino-3-phenylpropane With benzyl chloroformate; triethylamine in tetrahydrofuran T=20°C; 1.75 h; Inert atmosphereCooling with ice; 2: methylmagnesium bromide in tetrahydrofuran T=20°C; 24.1667 h; Inert atmosphereCooling with ice;
参考文献
Latorre, Antonio; Rodriguez, Santiago; Izquierdo, Javier; Gonzalez, Florenci V.
Tetrahedron Letters, 2009 , vol. 50, # 22 p. 2653 - 2655
反应条件
1: 1-amino-3-phenylpropane With p-nitrophenyl carbonate Merrifield resin; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; Solid phase reaction; 6 h; 2: acetyl-bromide With triethylamine; zinc dibromide in dichloromethane T=20°C; Solid phase reaction;
参考文献
Li; Lin; Yo
Tetrahedron Letters, 2000 , vol. 41, # 34 p. 6619 - 6622
反应条件
in tetrahydrofuran T=20°C; 24.1667 h; Inert atmosphereCooling with ice;
参考文献
Latorre, Antonio; Rodriguez, Santiago; Izquierdo, Javier; Gonzalez, Florenci V.
Tetrahedron Letters, 2009 , vol. 50, # 22 p. 2653 - 2655
反应条件
in tetrahydrofuran T=20°C; 24.1667 h; Inert atmosphereCooling with ice;
参考文献
Latorre, Antonio; Rodriguez, Santiago; Izquierdo, Javier; Gonzalez, Florenci V.
Tetrahedron Letters, 2009 , vol. 50, # 22 p. 2653 - 2655
反应条件
triethylamine; zinc dibromide in dichloromethane T=20°C; Solid phase reaction; Acetylation;
参考文献
Li, Wen-Ren; Yo, Ying-Chih; Lin, Yu-Sheng
Tetrahedron, 2000 , vol. 56, # 45 p. 8867 - 8875
反应条件
Rh(acac)(CO)2; hydrogen; toluene-4-sulfonic acid; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in diethylene glycol dimethyl ether T=100°C; P=37503.8 Torr; 8 h; Inert atmosphereSchlenk technique; chemoselective reaction;
参考文献
Raoufmoghaddam, Saeed; Drent, Eite; Bouwman, Elisabeth
ChemSusChem, 2013 , vol. 6, # 9 p. 1759 - 1773
