(S)-(+)-α-(三氟甲基)苄醇合成路线 （共 18 条）
反应条件
(S,S)-RuCl2(2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl)(1,1-dianisyl-2-isopropyl-1,2-ethylenediamine); potassium tert-butylate; hydrogen in isopropyl alcohol T=26 - 30°C; P=7600 Torr; 16 h;
参考文献
Ohkuma; Koizumi; Doucet; Pham; Kozawa; Murata; Katayama; Yokozawa; Ikariya; Noyori
Journal of the American Chemical Society, 1998 , vol. 120, # 51 p. 13529 - 13530
反应条件
anhydrous magnesium perchlorate; chiral bis(1,4-dihydronicotinamide) in chloroform; acetonitrile T=50°C; 11 h; influence of the chiral reagent; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 103, # 15 p. 4613 - 4615
反应条件
1: With C52H46I2O8; potassium phenolate in toluene T=-50°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Fluorine Chemistry, , vol. 130, # 8 p. 762 - 765
反应条件
chiral 2-(3',5'-di-t-butylPh)-2-phosphabicyclo[3.3.0]octane in n-heptane T=-20°C; 1 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 125, # 14 p. 4166 - 4173
反应条件
hydrogen fluoride; water in acetonitrile T=20°C;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 13-14 p. 1793 - 1796
反应条件
hydrogen in toluene T=20°C; Orito reaction; P=750.075 Torr; optical yield given as percent eeenantioselective reaction;
参考文献
Catalysis Communications, , vol. 12, # 15 p. 1410 - 1414
反应条件
hydrogen in toluene T=20°C; Orito reaction; P=750.075 Torr; optical yield given as percent eeenantioselective reaction;
参考文献
Catalysis Communications, , vol. 12, # 15 p. 1410 - 1414
反应条件
lipase from Pseudomonas cepacia immobilized on ceramic in toluene T=40°C; 15 h;
参考文献
Monatshefte fur Chemie, , vol. 134, # 8 p. 1151 - 1157
反应条件
Pseudomonas cepacia lipase; 4 A molecular sieve; peracetylated-β-cyclodextrin in toluene T=40°C; 8 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 17 p. 2547 - 2555
反应条件
n-butyllithium in hexane; toluene T=0°C; 16 h;
参考文献
Tetrahedron Letters, , vol. 47, # 16 p. 2821 - 2824
