1: in tetrahydrofuran T=18°C; 21.5 - 36 h; 2: With hydrogenchloride in tetrahydrofuran; dichloromethane; water T=40 - 56°C; 0.25 h; Product distribution / selectivity;
参考文献
PHARMACIA and UPJOHN COMPANY LLC
Patent: WO2007/10387 A2, 2007 ;
Location in patent: Page/Page column 37-38; 53-54 ;
1: in tetrahydrofuran T=18°C; 21.5 - 36 h; 2: With hydrogenchloride in tetrahydrofuran; dichloromethane; water T=40 - 56°C; 0.25 h; Product distribution / selectivity;
参考文献
PHARMACIA and UPJOHN COMPANY LLC
Patent: WO2007/10387 A2, 2007 ;
Location in patent: Page/Page column 37-38; 53-54 ;