2-(乙酰基氨基)-4-(甲基磺酰基)丁酸乙酯合成路线 （共 7 条）
反应条件
1: acetamide; carbon monoxide With hydrogen; dicobalt octacarbonyl in ethyl acetate T=80°C; P=97509.8 Torr; 0.0833333 h; 2: 3-methylsulfanyl-propionaldehyde in ethyl acetate T=80°C; P=97509.8 Torr; 2.5 h; Product distribution / selectivity;
参考文献
WO2005/121079 A1, ;
Page/Page column 12 ;
反应条件
1: acetamide; carbon monoxide With hydrogen; dicobalt octacarbonyl in ethyl acetate T=80°C; P=97509.8 Torr; 0.0833333 h; 2: 3-methylsulfanyl-propionaldehyde in ethyl acetate 2.5 h; Product distribution / selectivity;
参考文献
WO2005/121068 A1, ;
Page/Page column 11-12 ;
反应条件
TEA in dichloromethane T=25°C; 12 h;
参考文献
Damour, Dominique; Barreau, Michel; Blanchard, Jean-Charles; Burgevin, Marie-Claude; Doble, Adam; Pantel, Guy; Labaudiniere, Richard; Mignani, Serge
Chemistry Letters, 1998 , # 9 p. 943 - 944
反应条件
1: 100 percent / HCl / 3.5 h / 0 - 20 °C 2: 95 percent / TEA / CH2Cl2 / 12 h / 25 °C View Scheme
参考文献
Chemistry Letters, , # 9 p. 943 - 944
参考文献
Journal of Physical Chemistry, , vol. 57, p. 607
DE814445 , ;
DRP/DRBP Org.Chem.
反应条件
triethylamine in ethanol
参考文献
Hoffmann-LaRoche
Patent: GB836332 , 1960 ;
Chem.Abstr., 1961 , vol. 55, # 408
参考文献
Hoffmann-La Roche
Patent: DE1089390 , 1961 ;
Chem.Abstr., 1962 , vol. 56, # 4860
