1,3,5-吡唑-3,5-二羧酸三甲酯合成路线 （共 16 条）
反应条件
potassium carbonate in acetone 24 h; Heating;
参考文献
Denny; Atwell; Baguley; Wakelin
Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1568 - 1574
反应条件
hydrogenchloride T=60°C; 8 h;
参考文献
Vasilevskii, S. F.; Shvartsberg, M. S.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, # 5 p. 778 - 784
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 5 p. 1071 - 1077
反应条件
hydrogenchloride in methanol T=25 - 50°C;
参考文献
Tetrahedron Letters, , vol. 44, # 31 p. 5867 - 5870
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 126, p. 177,192
反应条件
1: 47 percent / KMnO4 / H2O / Heating 2: thionyl chloride / methanol / 24 h / Heating 3: K2CO3 / acetone / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 2 p. 428 - 431
反应条件
1: thionyl chloride / methanol / 24 h / Heating 2: K2CO3 / acetone / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 2 p. 428 - 431
反应条件
potassium carbonate in acetone 1 h; Heating; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 54, # 2 p. 428 - 431
反应条件
1: KMnO4 View Scheme
参考文献
Helvetica Chimica Acta, , vol. 41, p. 1898,1902
参考文献
Helvetica Chimica Acta, , vol. 41, p. 1898,1902
反应条件
1: 89 percent / KOH / methanol / 24 h / 20 °C 2: SOCl2 / 0.5 h / Heating 3: NaN3 / acetone; H2O / 0.02 h 4: toluene / 0.5 h / Heating 5: H2 / 5percent Pd/C / 0.5 h / 2660 Torr View Scheme
参考文献
Lee, Ho H.; Cain, Bruce F.; Denny, William A.; Buckleton, John S.; Clark, George R.
Journal of Organic Chemistry, 1989 , vol. 54, # 2 p. 428 - 431
