potassium hydrogen difluoride in methanol; water T=20°C; 0.5 h;

1: in tetrahydrofuran T=-78 - 0°C; 1.83333 h; 2: With potassium hydrogen difluoride; water in tetrahydrofuran T=0 - 20°C; 1.16667 h;

hydrogenchloride in methanol; diethyl ether; water Mg compd. added to soln. of B compd. at -65--70°C dropwise within1.5 h, warmed to 20°C within 3 h, hydrolysed with aq. HCl, org. phase sepd., aq. phase extd. with ether, dried with MgSO4, dissolved in MeOH, reacted with aq. B compd.; after 5 min filtered, dried, extd. with hot acetone, solvent removed in vac., dried over P4O10;

boron trifluoride diethyl etherate; copper diacetate in acetonitrile T=20°C;

palladium diacetate; potassium carbonate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in water; toluene T=80°C; Suzuki-Miyaura cross-coupling; 36 h;

water; silica gel T=20°C; 1 h; Inert atmosphere;