1,3-二氯-5-氯甲基苯合成路线 （共 9 条）
反应条件
phosphorus pentachloride
参考文献
Monatshefte fuer Chemie, , vol. 62, p. 344,347
反应条件
1: LiAlH4 / tetrahydrofuran / 0 °C / r.t., overnight 2: SOCl2 / 2 h / reflux View Scheme
参考文献
Pest Management Science, , vol. 56, # 10 p. 875 - 881
反应条件
1: aqueous KOH-solution 2: PCl5 View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 62, p. 344,347
反应条件
1: dimethylsulfoxide / 5 h / 40 - 50 °C 2: 25 percent NaOH / ethanol / Heating View Scheme
参考文献
Taylor, David C.; Wightman, Frank; Kazakoff, Clem W.
Phytochemistry (Elsevier), 1988 , vol. 27, # l p. 51 - 72
反应条件
potassium cyanide in dichloromethane; water; toluene
参考文献
THE WELLCOME FOUNDATION LIMITED
Patent: EP459819 A2, 1991 ;
反应条件
in ethanol; water Heating;
参考文献
Sorensen, Esben R.; El-Brollosy, Nasser R.; Jorgensen, Per T.; Pedersen, Erik B.; Nielsen, Claus
Archiv der Pharmazie, 2005 , vol. 338, # 7 p. 299 - 304
反应条件
hydrogenchloride; sodium ethanolate 1.) ethanol, reflux, 12 h, 2.) reflux, 12 h; Yield given. Multistep reaction;
参考文献
Brunner, Henri; Hankofer, Peter; Holzinger, Ulrich; Treittinger, Barbara; Schoenenberger, Helmut
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 1 p. 35 - 44
反应条件
1: ethanol / 3 h / Heating
2: 10 N aq. NaOH / 0.33 h / 70 °C
View Scheme
参考文献
Brown, Thomas J.; Chapman, Robert F.; Cook, David C.; Hart, Terance W.; McLay, Iain M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 20 p. 3613 - 3624
反应条件
hydrazine in methanol
2 h; Ambient temperature;
参考文献
Finneman, Jari I.; Fishbein, James C.
Journal of the American Chemical Society, 1995 , vol. 117, # 15 p. 4228 - 4239
