4-氯乙酰乙酸甲酯合成路线

Gyoten, Michiyo; Nagaya, Hideaki; Fukuda, Shigeru; Ashida, Yasuko; Kawano, Yasuhiko
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 2 p. 122 - 133

640-68-6D-缬氨酸

参考文献

The DuPont Merck Pharmaceutical Company
Patent: US5773411 A1, 1998 ;

4128-31-8仲辛醇+

32807-28-64-氯乙酰乙酸甲酯

5978-70-1(R)-(-)-2-辛醇+

88496-70-2(R)-4-氯-3-羟基丁酸甲酯

参考文献

Bisogno, Fabricio R.; Lavandera, Ivan; Kroutil, Wolfgang; Gotor, Vicente
Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1730 - 1732

32807-28-64-氯乙酰乙酸甲酯+

98-85-1DL-1-苯乙醇

1445-91-6(S)-(-)-1-苯基乙醇+

86728-93-0(S)-4-氯-3-羟基丁酸甲酯

参考文献

Bisogno, Fabricio R.; Lavandera, Ivan; Kroutil, Wolfgang; Gotor, Vicente
Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1730 - 1732

32807-28-64-氯乙酰乙酸甲酯

88496-70-2(R)-4-氯-3-羟基丁酸甲酯+

86728-93-0(S)-4-氯-3-羟基丁酸甲酯

参考文献

Ushio, Kazutoshi; Inouye, Kiyoko; Nakamura, Kaoru; Oka, Shinzaburo; Ohno, Atsuyoshi
Tetrahedron Letters, 1986 , vol. 27, # 23 p. 2657 - 2660