1-溴-4-苯基-2-丁酮合成路线 （共 12 条）
反应条件
bromine in methanol; hexane; water
参考文献
Gutman, Arie; Nisnevich, Gennadiy; Etinger, Marina; Zaltzman, Igor; Judovich, Lev; Pertsikov, Boris
Patent: US2003/149294 A1, 2003 ;
反应条件
1: in tetrahydrofuran; hexane T=0°C; 3.1 h; 2: With hydrogen bromide in water; acetic acid T=0°C; 0.166667 h;
参考文献
MYRIAD GENETICS, INC.
Patent: WO2007/38684 A2, 2007 ;
Location in patent: Page/Page column 41 ;
反应条件
hydrogen bromide in diethyl ether
参考文献
Ackrell; Franco; Greenhouse; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 5 p. 1081 - 1085
反应条件
Oxonereg;; NH4Br in methanol 0.5 h; Reflux; regioselective reaction;
参考文献
Tetrahedron Letters, , vol. 53, # 2 p. 191 - 195
反应条件
2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; water in 1,2-dichloro-ethane T=20°C; 14 h;
参考文献
Xie, Longyong; Wu, Yundong; Yi, Weiguo; Zhu, Lei; Xiang, Jiannan; He, Weimin
Journal of Organic Chemistry, 2013 , vol. 78, # 18 p. 9190 - 9195
反应条件
(i) Et2O, (ii) HBr; Multistep reaction;
参考文献
Chemische Berichte, , vol. 96, p. 465 - 469
反应条件
1: 57 percent / potassium carbonate / methanol / 16 h / Heating 2: 58 percent / bromine / methanol / 2 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 9 p. 3225 - 3234
反应条件
1: diethyl ether / 0 °C 2: 85 percent / Hydrogen bromide / diethyl ether View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 17, # 5 p. 1081 - 1085
反应条件
1: Thionyl chloride / 4 h / Heating 2: diethyl ether / 0 °C 3: 85 percent / Hydrogen bromide / diethyl ether View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 17, # 5 p. 1081 - 1085
反应条件
n-butyllithium; lithium diisopropyl amide Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 50, # 25 p. 5140 - 5142
