1,4-二氢-6-甲氧基-7-异丙氧基-4-氧代-3-喹啉甲腈合成路线 (共 8 条)
反应条件
in diphenylether T=225°C; 0.5 h; Microwave irradiation;
参考文献
Cao, Xin; You, Qi-Dong; Li, Zhi-Yu; Yang, Yan; Wang, Xiao-Jian
Synthetic Communications, 2009 , vol. 39, # 24 p. 4375 - 4383
反应条件
1.1: HNO3 2.1: Fe; NH4Cl 3.2: n-BuLi View Scheme
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
1.1: HNO3 2.1: Fe; NH4Cl 3.2: n-BuLi View Scheme
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
1.1: Fe; NH4Cl 2.2: n-BuLi View Scheme
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
1: N,N-dimethyl-formamide dimethyl acetal; methyl 2-amino-4-isopropoxy-5-methoxybenzoate Condensation; Cyclization; 2: acetonitrile With n-butyllithium
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
1: POCl3 2: AlCl3 View Scheme
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
1: POCl3
2: AlCl3
3: DEAD; PPh3
View Scheme
参考文献
Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480
反应条件
trichlorophosphate
4 h; Heating;
参考文献
Cao, Xin; You, Qi-Dong; Li, Zhi-Yu; Guo, Qing-Long; Shang, Jing; Yan, Ming; Chern, Ji-Wang; Chen, Men-Ling
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 11 p. 5890 - 5898