in acetonitrile T=23°C; half-live value, other amino alcohols as serine protease mimic, other substrate: p-nitro-2,2,2-trifluoroacetanilide, other temperature; Mechanism;
参考文献
Madder, Annemieke; De Clercq, Pierre J.; Declercq, Jean-Paul
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2548 - 2559
1: With di-isopropyl azodicarboxylate; triphenylphosphine in dichloromethane T=0 - 20°C; 16 h; 2: With hydrogenchloride in water 3: With potassium carbonate in water
参考文献
Breitenbucher, J. Guy; Lee-Dutra, Alice; Neff, Danielle K.
Patent: US2006/4039 A1, 2006 ;
Location in patent: Page/Page column 14 ;